Hostname: page-component-848d4c4894-nr4z6 Total loading time: 0 Render date: 2024-06-09T18:02:39.655Z Has data issue: false hasContentIssue false
  • English
  • Français

Detection of diphtheria toxin antibodies in human sera in New Zealand by ELISA

Published online by Cambridge University Press:  19 October 2009

R. C. H. Lau
R. C. H. Lau
Affiliation:
Immunology Research and Development Unit, National Health Institute, Kenepuru Drive, Porirua, Wellington, New Zealand
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

An enzyme-linked immunosorbent assay (ELISA) was developed to detect IgG antibodies to diphtheria toxin in human serum. Serum samples obtained from 557 normal persons aged 1–65 years from different areas in New Zealand showed maximum antibody levels in the 1–9 years age group (95·1%) and the least in the 60–65 years age group (38·1%). The indirect ELISA is suitable for sero-epidemiological survey study as it is simple to perform, economical and precise.

Type
Research Article
Information
Journal of Hygiene , Volume 96 , Issue 3 , June 1986 , pp. 415 - 418
Copyright
Copyright © Cambridge University Press 1986

References

REFERENCES

Bojlen, K. N.. & Scheibel, I. (1955). The duration of immunity following diphtheria vaccination. Danish Medical Bulletin 2, 70–73.Google ScholarPubMed
Gottlieb, S., Martin, M. & McLaughlin, F. X. (1967). Long term immunity to diphtheria and tetanus: a mathematical model. American Journal of Epidemiology 85, 207–219.CrossRefGoogle ScholarPubMed
Kjeldsen, K., Simonsen, O. & Heron, I. (1985). Immunity against diphtheria 25–30 years after primary vaccination in childhood. Lancet i, 900–902.CrossRefGoogle Scholar
Maclean, F. S. (1964). The history of diphtheria. In Challenge for Health, pp. 345–359. Wellington: Owen.Google Scholar
Mathias, R. G. & Schechter, M. T. (1985). Booster immunisation for diphtheria and tetanus: no evidence of needs in adults. Lancets i, 1089–1090.CrossRefGoogle Scholar
Scheibel, I., Bentzon, M. W., Christensen, P. E. & Biering, A. (1966). Duration of immunity to diphtheria and tetanus after active immunization. Acta Pathologica et Microbiologica Scandinavica 67, 380–392.CrossRefGoogle ScholarPubMed
Scheibel, I., Bentzon, M. W., Tulinius, S. & Bojlen, K. (1962). Duration of immunity to diphtheria and tetanus after active immunization. Acta Pathologica et Microbiologica Scandinavica 55, 483–495.CrossRefGoogle ScholarPubMed
The Public Health (1983). Report of the Department of Health for the year ended 31 03 1983, p. 72. Wellington: Hasselberg.Google Scholar
Trinca, J. C. (1975). Combined diphtheria-tetanus immunization of adults. Medical Journal of Australia 2, 543–546.CrossRefGoogle ScholarPubMed