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Factors influencing oral carriage of yeasts among individuals with diabetes mellitus

Published online by Cambridge University Press:  15 May 2009

F. Z. Aly ,
C. C. Blackwell ,
D. A. C. Mackenzie ,
D. M. Weir  and
B. F. Clarke
F. Z. Aly
Affiliation:
Department of Medical Microbiology, University of Edinburgh, Medical School Building, Teviot Place, Edinburgh EH8 9AG
C. C. Blackwell
Affiliation:
Department of Medical Microbiology, University of Edinburgh, Medical School Building, Teviot Place, Edinburgh EH8 9AG
D. A. C. Mackenzie
Affiliation:
Department of Medical Microbiology, University of Edinburgh, Medical School Building, Teviot Place, Edinburgh EH8 9AG
D. M. Weir
Affiliation:
Department of Medical Microbiology, University of Edinburgh, Medical School Building, Teviot Place, Edinburgh EH8 9AG
B. F. Clarke
Affiliation:
Department of Medical Microbiology, University of Edinburgh, Medical School Building, Teviot Place, Edinburgh EH8 9AG
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A total of 439 individuals with diabetes mellitus were examined for carriage of yeasts by the oral rinse and palatal swab techniques. Eighteen genetic or environment variables were assessed for their contribution to carriage of yeasts. The factor contributing to palatal and oral carriage of yeasts among individuals with insulin dependent diabetes mellitus (IDDM) was age (P < 0·01). The factor contributing to palatal carriage of yeasts among individuals with non-insulin dependent diabetes mellitus (NIDDM) was poor glycaemic control (glycosuria P < 0·01); carriage in the oral cavity as a whole was influenced additionally by non-secretion of ABH blood group antigens (P < 0·05). Introduction of a denture altered the above risk factors. For individuals with IDDM, oral carriage was associated with the presence of retinopathy (P < 0·05); palatal carriage was influenced by poor glycaemic control (HbA1P < 0·01, plasma glucose levels P < 0·05) and age (P < 0·05). For those with NIDDM, palatal carriage was associated with continuous presence of the denture in the mouth (P < 0·01); oral carriage was associated with plasma glucose levels (P < 0·05).

Type
Research Article
Information
Epidemiology & Infection , Volume 109 , Issue 3 , December 1992 , pp. 507 - 518
Copyright
Copyright © Cambridge University Press 1992

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