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Further Experiences with Intravenous Antitoxin Treatment of Scarlet Fever

Published online by Cambridge University Press:  15 May 2009

H. Stanley Banks
Affiliation:
Medical Superintendent, Park Hospital, Hither Green, London. Late Medical Superintendent, City of Leicester Isolation Hospital and Sanatorium.
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1. Experience of 4½ years of intravenously administered scarlatinal antitoxin, in 1204 cases, confirms the tentative conclusions reached in 1928, viz. that the acute stage of the disease can generally be arrested in 12–24 hours, complications almost wholly prevented, and the period of morbidity reduced to a little over a fortnight.

2. These effects were obtained in hospital wards where over 50 per cent, of the cases, generally about 75 per cent, and including all the worst, were so treated, and it is possible that the reduction of mass infection obtained in the wards by this means is an essential condition for obtaining such results. Under such conditions relapses and cross-infections were very rare.

3. Some evidence was obtained that intravenous antitoxin administered in the acute stage of scarlet fever largely prevents the onset of septic complications, including the late septic type itself, scarlatina anginosa; and that it may be of striking benefit in the treatment of the septic type, even at a late stage.

4. The importance of proved clinical potency and freedom from dangerous reactions of each individual batch of serum to be employed, is stressed.

5. Indications and contra-indications are stated.

6. Certain precautions and details of technique are recommended.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1933

References

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