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The inhibitory action of the monoethyl esters of S-n-alkylthiomalic acids and the monoethyl esters of alkane sulphonyl succinic acids on the growth of Mycobacterium tuberculosis

Published online by Cambridge University Press:  15 May 2009

P. A. McNally
P. A. McNally
Affiliation:
From the School of Pathology, Trinity College, Dublin
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1. A new series of compounds has been found which markedly inhibits the growth of Mycobacterium tuberculosis and M. smegmatis.

2. These substances are strongly haemolytic against human red blood cells.

3. The effectiveness of the antibacterial and haemolytic actions depends upon the length of the alkyl chain.

4. The antibacterial and haemolytic actions are reduced by human serum.

Type
Research Article
Information
Journal of Hygiene , Volume 46 , Issue 1 , March 1948 , pp. 60 - 61
Copyright
Copyright © Cambridge University Press 1948

References

REFERENCES

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Feldman, W. H. (1946). J. Inst. Publ. Hlth Hyg. 9, no. 10, p. 297.Google Scholar
McNally, P. A. (1947). Brit. J. Exp. Path. 28, 161.Google Scholar