Hostname: page-component-5c6d5d7d68-wp2c8 Total loading time: 0 Render date: 2024-08-25T17:16:51.534Z Has data issue: false hasContentIssue false
  • English
  • Français

The isolation of an unclassified virus from an outbreak of infantile diarrhoea

Published online by Cambridge University Press:  15 May 2009

A. M. Murphy
A. M. Murphy
Affiliation:
The Institute of Clinical Pathology and Medical Research, Lidcombe, New South Wales
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

A virus was isolated from fifteen of nineteen children living in an infants' home during an outbreak of diarrhoea. The virus possesses many of the characteristics of the enterovirus group but is serologically distinct from any of the accepted members of this group. It is non-pathogenic for unweaned mice, non-cytopathic in tissue cultures of monkey kidney, but is rapidly cytopathic for tissue-cultured cells of human origin. It is serologically similar to virus Hu 659 isolated by Abrahams in the United States (personal communication).

I should like to thank the Director-General of Public Health and State Psychiatric Services, New South Wales, for permission to publish.

Type
Research Article
Information
Journal of Hygiene , Volume 62 , Issue 4 , December 1964 , pp. 425 - 432
Copyright
Copyright © Cambridge University Press 1964

References

REFERENCES

Abrahams, A. S. (1963). Isolation and properties of a human enterovirus, non-pathogenic for monkey kidney cell cultures and suckling mice. Proc. Soc. exp. Biol., N.Y., 112, 743.CrossRefGoogle Scholar
Cooney, M. K., McLaren, L. C. & Bauer, H. (1962). A newly recognized enterovirus with affinity for primary human amnion cells isolated from cases of aseptic meningitis. Amer. J. Hyg. 75, 301.Google ScholarPubMed
Duncan, I. B. R. (1960). Aseptic meningitis associated with a previously unrecognised virus. Lancet, ii, 470.CrossRefGoogle Scholar
Goldfield, M., Srihongse, S. & Fox, J. F. (1957). Haemagglutinins associated with certain human enteric viruses. Proc. Soc. exp. Biol., N.Y., 96, 788.CrossRefGoogle ScholarPubMed
Joncas, J. & Pavilanis, V. (1960). Diarrhoea and vomiting in infancy and childhood. Viral studies. Canad. med. Ass. J., 82, 1108.Google ScholarPubMed
Ketler, A., Hamparian, V. V. & Hilleman, M. R. (1962). Characterisation and classification of ECHO 28–Rhinovirus-Coryzavirus agents. Proc. Soc. exp. Biol., N.Y., 110, 821.CrossRefGoogle ScholarPubMed
Moorhead, P. S. & Hayflick, L. (1961). The serial cultivation of human diploid cell strains. Exp. Cell Res. 25, 585.Google Scholar
Ramos-Alvarez, M. & Sabin, A. B. (1958). Entero-pathogenic viruses and bacteria. Role in summer diarrhoeal diseases of infancy and early childhood. J. Amer. med. Ass. 167, 147.CrossRefGoogle Scholar
Sommerville, R. G. (1958). Enteroviruses and diarrhoea in young persons. Lancet, ii, 1347.CrossRefGoogle Scholar
Walker, S. J., McLean, D. M., Roy, T. E., McNaughton, G. A. & Tibbles, J. A. R. (1960). Infantile gastroenteritis: A search for viral pathogens. Canad. med. Ass. J. 83, 266.Google ScholarPubMed
Yow, M. D., Melnick, J. L., Blattner, R. J. & Rasmussen, L. E. (1963). Enteroviruses in infantile diarrhoea. Amer. J. Hyg. 77, 283.Google Scholar