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Lymphoproliferative response to fusion proteins of human papillomaviruses in patients with cervical intraepithelial neoplasia

Published online by Cambridge University Press:  15 May 2009

H. A. Cubie ,
M. Norval ,
L. Crawford ,
L. Banks  and
T. Crook
H. A. Cubie
Affiliation:
Department of Bacteriology, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG
M. Norval*
Affiliation:
Department of Bacteriology, University of Edinburgh Medical School, Teviot Place, Edinburgh EH8 9AG
L. Crawford
Affiliation:
Laboratory of Molecular Virology, Imperial Cancer Research Fund, Lincoln's Inn Fields, London WC2A 3PX
L. Banks
Affiliation:
Laboratory of Molecular Virology, Imperial Cancer Research Fund, Lincoln's Inn Fields, London WC2A 3PX
T. Crook
Affiliation:
Laboratory of Molecular Virology, Imperial Cancer Research Fund, Lincoln's Inn Fields, London WC2A 3PX
*
*Author for correspondence.
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Summary

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The cell-mediated immune response (CMI) to E6 and E4 fusion proteins of human papillomavirus type 16 (HPV-16), E6 fusion protein of HPV-18, and to control proteins similarly produced, was analysed in 29 patients with cervical intraepithelial neoplasia (CIN) and in 15 age-matched laboratory personnel using a lymphocyte proliferation assay (LPA).

Type
Research Article
Information
Epidemiology & Infection , Volume 103 , Issue 3 , December 1989 , pp. 625 - 632
Copyright
Copyright © Cambridge University Press 1989

References

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