Hostname: page-component-7479d7b7d-767nl Total loading time: 0 Render date: 2024-07-10T09:53:01.993Z Has data issue: false hasContentIssue false

Microorganisms and their Relation to Fever1

Published online by Cambridge University Press:  15 May 2009

E. C. Hort
Affiliation:
(From the Lister Institute, London.)
W. J. Penfold
Affiliation:
(From the Lister Institute, London.)
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

It appears to be widely believed that the fever of infective disease is due to absorption of phyrogenetic substances liberated from dead microorganisms by a combuined process of lysis and extraction in the body of the infected subject. The diffusion of products of the action of bacterial autolytic enzymes on microorganisms after their destruction by the defensive agencies of the body is a variant on the same theme. Closely allied are the theories of protein fever, and of anaphylactic fever, in so far as they relate to the supposed possession by microorganisms, or their split products, of pyrogenetic properties. The absorption of alien protein, or of derivatives of alien protoplasm, from organisms that are dead, is, in short, the essential feature of this conception of fever production.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1912

References

REFERENCES

(1)Hort, E. C. (1909). Rational Immunization in the Treatment of Pulmonary Tuberculosis. Bale, Sons and Danielsson, London.Google Scholar
(2)Hort, E. C. and Penfold, W. J. (1911). The Dangers of Saline Injections. British Medical Journal, 1911, II. 1510.Google Scholar
Hort, E. C. and Penfold, W. J.The Relation of Salvarsan Fever to other forms of infectious Fever. Proc. of Roy. Soc. of Med., 1912, V. 1911 et seq.Google Scholar
Hort, E. C. and Penfold, W. J.A critical study of experimental Fever. Proc. of Roy. Soc. B, LXXXV. 1912.Google Scholar
(2 a)Vaughan, V. C., Cumming, J. G. and Wright, J. H.Protein Fever. Zeitsch. f. Immunitätsforsch. und experimentelle Therapie. Pt. 1. Orig. IX. 458.Google Scholar
(2 b)Vaughan, Wheeler Gidley (1909). Protein Fever. Journal of the American Medical Association.CrossRefGoogle Scholar
(2 c)Friedberger, E. and Mita, S. (1911). Ueber Anaphylaxie. Die Anaphylaktische Fieberreaktion. Zeit. f. Immun., Pt. 1, 216.Google Scholar
(2 d)Schittenhelm, A., Weichardt, W. und Hartmann, F. (1912). Ueber die Beeinflussung der Körpertemperatur durch parenterale Einverleitung von Proteinsubstanzen verschiedenes Herkunft. Zeit. f. exp. Path. und Ther., X. 448.Google Scholar
(3)Friedberger, E.Anaphylaktische Fieber. Berlin klin. Woch. (1910), No. 42.Google Scholar
(4)Hort, E. C.Autotoxaemia and Infection. Proc. Roy. Soc., 1910, LXXXII. 529545.Google Scholar