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Published online by Cambridge University Press: 15 May 2009
Several attempts have been made at various times to obtain a mathematical expression of the relation between dosage, body weight and death time. The subject has recently gained importance through the interesting publications of Dreyer and Walker, who have put forward such a formula, and have illustrated its application to toxicity determinations for a number of substances, and, in particular, for different samples of diphtheria toxin—a matter of considerable practical importance. I propose to examine the theoretical basis of their formula, and its relation to formulae which other workers have suggested, and to criticise the evidence with which they have illustrated its application to experimental material.
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page 380 note 1 Dr Ainley Walker has kindly pointed out to me that this misprint was corrected in the next number of the Biochemische Zeitschrift.
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