Hostname: page-component-84b7d79bbc-c654p Total loading time: 0 Render date: 2024-07-30T06:20:10.254Z Has data issue: false hasContentIssue false
  • English
  • Français

The pathogenicity of environmental campylobacters-a human volunteer experiment

Published online by Cambridge University Press:  15 May 2009

S. L. Mawer
S. L. Mawer
Affiliation:
Public Health Laboratory, Hull Royal Infirmary, Anlaby Road, Hull HU3 2JZ, UK
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Three human volunteer experiments were performed in which river water expected to contain campylobacter organisms was ingested. Despite the ingestion of over 44000 organisms in one experiment, the subject did not suffer any symptoms, nor were campylobacter organisms excreted, nor was an antibody response to the ingested strains detected. The campylobacter organisms ingested resembled Campylobacter jejuni on colonial and microscopic morphology but were hippurate negative, and were distinct from C. coli. These environmental campylobacter strains appear to be non-pathogenic, however they may be mistaken for C. Jejuni or C.coli if they are not fully identified.

Type
Research Article
Information
Epidemiology & Infection , Volume 101 , Issue 2 , October 1988 , pp. 295 - 300
Copyright
Copyright © Cambridge University Press 1988

References

Black, R. E. (1983). Studies of Campylobacter jejuni infection in volunteers. In Campylobacter II, Proceedings of the Second International Workshop on Campylobacter Infections (ed. Pearson, A. D.Skirrow, M. B.Rowe, B.Davies, J.Jones, D. M.). London: Public Health Laboratory Service.Google Scholar
Bolton, F. J. & Robertson, L. (1982). A selective medium for isolating Campylobacter jejuni/ coli. Journal of Clinical Pathology 35, 462–467.CrossRefGoogle ScholarPubMed
Editorial, (1983). New faces among the campylobacters. Lancet ii, 662.Google Scholar
Jones, D. M., Robinson, D. A. & Eldridge, J. (1981). Serological studies in two outbreaks of Campylobacter jejuni infection. Journal of Hygiene 87, 163–170.CrossRefGoogle ScholarPubMed
Mccoy, J. H. (1961). The isolation of Salmonellae. Journal of applied Bacteriology 25, 213.CrossRefGoogle Scholar
Mccoy, J. H. (1971). Sewage pollution of natural waters. In Microbial Aspects of Pollution. Society for Applied Bacteriology. Symposium Series No. 1. London and New York. Academic Press.Google Scholar
Mawer, S. L. (1988). Campylobacters in man and the environment in Hull and East Yorkshire. Epidemiology and Infection 101, 287–294CrossRefGoogle ScholarPubMed
Mentzing, L. O. (1982). A water-borne outbreak of. campylobacter in central Sweden. In Campylobacter, Epidemiology, Pathogenesis and Biochemistry (ed. Newell, D. G.). London: Public Health Laboratory Service.Google Scholar
Morris, G. K., el Sherbeeny, M. R., Patton, C. M., Kodaka, H., Lombard, G. I., Edmonds, P., Hollis, D. G. & Brenner, D. J. (1985). Comparison of four hippurate hydrolysis methods for identification of thermophilie Campylobacter spp. Journal of Clinical Microbiology 22, 714–718.CrossRefGoogle Scholar
Penner, J. L. & Hennessy, J. N. (1980). Passive haemagglutination technique for serotyping Campylobacter fetus subsp. jejuni on the basis of soluble heat stable antigens. Journal of Clinical Microbiology 12, 732–737.CrossRefGoogle ScholarPubMed
Robinson, D. A. (1981). Infective dose of Campylobacter jejuni in milk. British Medical, Journal 282, 1584.CrossRefGoogle ScholarPubMed
Skirrow, M. B. (1977). Campylobacter enteritis: a ‘new’ disease. British Medical Journal 2, 9–11.CrossRefGoogle ScholarPubMed
Skirrow, M. B. & Benjamin, J. (1980a). Differentiation of enteropathogenic campylobacter. Journal of Clinical Pathology 33, 1122.CrossRefGoogle ScholarPubMed
Skirrow, M. B. & Benjamin, J. (1980b). ‘1001’ campylobacters: cultural characteristics of intestinal campylobacters from man and animals. Journal of Hygiene, 84, 427–442.CrossRefGoogle Scholar