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The reduction of the carcinogenic and dermatitic activity of shale oil recovered from the peritoneal cavities of injected mice

Published online by Cambridge University Press:  15 May 2009

J. M. Twort  and
R. Lyth
J. M. Twort
Affiliation:
The Laboratories of the Manchester Committee on Cancer
R. Lyth
Affiliation:
The Laboratories of the Manchester Committee on Cancer
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1. A carcinogenic Persian spindle grade oil recovered after 4 days from the peritoneal cavities of injected rabbits showed indications of reduced carcinogenic activity for the skins of mice.

2. The activity of a carcinogenic shale oil recovered after 7 days from the peritoneal cavities of injected mice was found to be considerably reduced. The reduction in refractive index and potency of the recovered shale oil showed an obvious parallel to that resulting from certain chemical treatments, namely, treatment of the oil with a certain quantity of sulphuric acid or extraction with alcohol.

Type
Research Article
Information
Journal of Hygiene , Volume 40 , Issue 4 , July 1940 , pp. 434 - 438
Copyright
Copyright © Cambridge University Press 1940

References

REFERENCES

Lyth, R. (1933). The relation of carcinogenicity of mineral oils to certain physical and chemical characteristics of these oils. J. industr. Hyg. 15, 226–37.Google Scholar
Polson, C. J. (1931). Experimental liver necrosis from shale oil. J. Path. Bact. 34, 5–12.CrossRefGoogle Scholar
Twort, C. C. & Fulton, J. D. (1929). Experiments on the nature of carcinogenic agents in mineral oils. J. Path. Bact. 32, 149–61.CrossRefGoogle Scholar
Twort, C. C. & Ing, H. R. (1928). Mule-spinners' cancer and mineral oils. Lancet, 1, 752–4.CrossRefGoogle Scholar
Twort, C. C. & Lyth, R. (1935 a). A new method for measuring carcinogenicity. J. Hyg., Camb., 35, 125–30.CrossRefGoogle ScholarPubMed
Twort, C. C. & Lyth, R. (1935 b). The violence of reaction of the animal in relation to the etiology of cancer and inflammation. J. Hyg., Camb., 35, 404–11.CrossRefGoogle Scholar
Twort, C. C. & Twort, J. M. (1933). Suggested methods for standardization of carcinogenic activity of different agents for skin of mice. Amer. J. Cancer, 17, 293–320.Google Scholar