Hostname: page-component-78c5997874-dh8gc Total loading time: 0 Render date: 2024-11-17T19:51:08.831Z Has data issue: false hasContentIssue false
  • English
  • Français

The relationship between therapeutic injections and high prevalence of hepatitis C infection in Hafizabad, Pakistan

Published online by Cambridge University Press:  01 December 1997

S. P. LUBY ,
K. QAMRUDDIN ,
A. A. SHAH ,
A. OMAIR ,
O. PAHSA ,
A. J. KHAN ,
J.B. McCORMICK ,
F. HOODBHOUY  and
S. FISHER-HOCH
S. P. LUBY
Affiliation:
Community Health Sciences Department, Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
K. QAMRUDDIN
Affiliation:
Pathology Department, Aga Khan University, Karachi, Pakistan
A. A. SHAH
Affiliation:
Aga Khan Health Services, Pakistan
A. OMAIR
Affiliation:
Community Health Sciences Department, Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
O. PAHSA
Affiliation:
Community Health Sciences Department, Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
A. J. KHAN
Affiliation:
Community Health Sciences Department, Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
J.B. McCORMICK
Affiliation:
Community Health Sciences Department, Aga Khan University, PO Box 3500, Stadium Road, Karachi, Pakistan
F. HOODBHOUY
Affiliation:
Aga Khan Health Services, Pakistan
S. FISHER-HOCH
Affiliation:
Pathology Department, Aga Khan University, Karachi, Pakistan
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

To determine the prevalence and routes of transmission of hepatitis C virus (HCV) infection in Hafizabad, Pakistan, we collected sera in 1993 from a geographically based random sample of residents, and in 1994 identified 15 HCV-infected individuals (cases) and 67 age and sex matched uninfected individuals (controls). Initially we approached 504 households, and collected serum from a randomly selected household member in 309 (64%). Twenty persons (6·5%) had anti-HCV antibody; 31% percent had hepatitis B core antibodies, and 4·3% had hepatitis B surface antigen. In the case-control study, persons who received more therapeutic injections (categorized as averaging 1, 2–4, 5–9 or >10 injections per year in the previous 10 years) were more likely to be infected with HCV (odds ratio 0, 1·5, 2·5 and 6·9 respectively, P=0·008) compared to persons averaging 0 injections per year. Efforts to limit therapeutic injections to only those that are medically indicated and that use sterile equipment are essential in order to prevent transmission of HCV.

Type
Research Article
Information
Epidemiology & Infection , Volume 119 , Issue 3 , December 1997 , pp. 349 - 356
Copyright
© 1997 Cambridge University Press