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Reservoir animals for nephropathia epidemica in Norway: indications of a major role for the bank vole (C. glareolus) in comparison with the woodmouse (A. sylvaticus)

Published online by Cambridge University Press:  19 October 2009

Ann-Inger Sommer ,
T. Traavik ,
R. Mehl ,
B. P. Berdal  and
J. M. Dalrymple
Ann-Inger Sommer
Affiliation:
Institute of Medical Biology, University of Tromso, and the Virological Laboratory, Regional Hospital of Tromso, Norway
T. Traavik
Affiliation:
Institute of Medical Biology, University of Tromso, and the Virological Laboratory, Regional Hospital of Tromso, Norway
R. Mehl
Affiliation:
Laboratory for Medical Entomology, National Institute of Public Health, Oslo, Norway
B. P. Berdal
Affiliation:
Norwegian Defence Microbiological Laboratory, Oslo, Norway
J. M. Dalrymple
Affiliation:
U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fredrick, Maryland, U.S.A.
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Summary

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Small rodents were collected live in two different locations within a nephropathia epidemica (NE) endemic area, and tested for both antiviral serum antibodies and viral antigens in lung sections. In one location, only Apodemus sylvaticus (woodmice) were found in the traps, in the other, both A. sylvaticus and Clethrionomys glareolus (bank voles) were collected.

Among the woodmice from the former location the prevalence of NE virus markers was significantly lower than for either woodmice or bank voles from the other location, and no NE antigen-positive animals was found. The woodmice co-existing with bank voles had a lower prevalence of NE antigen and antibodies than the bank voles, and fewer woodmice had both antibodies and antigen. The results emphasize the important role of bank voles as a major NE virus reservoir and probable source of human infections.

Type
Research Article
Information
Journal of Hygiene , Volume 94 , Issue 1 , February 1985 , pp. 123 - 127
Copyright
Copyright © Cambridge University Press 1985

References

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