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Seroepidemiology of Helicobacter pylori infection in vegans and meat-eaters

Published online by Cambridge University Press:  15 May 2009

M. J. Webberley ,
J. M. Webberley ,
D. G. Newell ,
P. Lowe  and
V. Melikian
M. J. Webberley
Affiliation:
Dudley Road Hospital, Birmingham
J. M. Webberley*
Affiliation:
Sandwell District Hospital, West Bromwich
D. G. Newell
Affiliation:
PHLS, Centre for Applied Microbiology and Research, Porton Down, Salisbury
P. Lowe
Affiliation:
Dudley Road Hospital, Birmingham
V. Melikian
Affiliation:
Dudley Road Hospital, Birmingham
*
*Author for correspondence and reprint requests: Dr J. M. Webberley, Department of Microbiology, Worcester Royal Infirmary, Castle St, Worcester WR1 3AS, UK.
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Summary

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An enzyme-linked immunosorbent assay has been used to diagnose serologically the prevalence of Helicobacter pylori infection in Asian life-long vegans. There was no difference in the seropositivity between these individuals and a group of age-and sex-matched Asian meat-eaters, indicating the meat consumption is not a risk factor for H. pylori infection. However, both Asian groups had a higher prevalence of infection than age- and sex-matched Caucasian meat-eaters. Additionally, the Asian individuals had a wider range of specific IgG antibody concentrations than the Caucasians. This did not appear to be due to antigenic cross-reactivity between H. pylori and Campylobacter jejuni. The significance of these observations to the establishment of cut-off levels for the serodiagnosis of certain ethnic groups is discussed.

Type
Research Article
Information
Epidemiology & Infection , Volume 108 , Issue 3 , June 1992 , pp. 457 - 462
Copyright
Copyright © Cambridge University Press 1992

References

REFERENCES

1.Drum, B, Perez-Perez, GI, Blaser, MJ, Sherman, PM. Intrafamilial clustering of Helicobacter pylori infection. N Eng J Med 1990; 322: 359–63.CrossRefGoogle Scholar
2.Berkowicz, J, Lee, A. Person-to-person transmission of Campylobacter pylori. Lancet 1987; ii: 680–1.CrossRefGoogle Scholar
3.Marshall, BJ, Armstrong, JA, McGechie, DB, Clancy, RJ. Attempt to fulfil Koch's postulates for pyloric Campylobacter. Med J Aust 1985; 142: 436–9.CrossRefGoogle ScholarPubMed
4.Morris, A, Nicholson, G. Ingestion of Campylobacter pyloridis causes gastritis and raised fasting pH. Am J Gastroenterol 1987; 82: 192–9.Google ScholarPubMed
5.Graham, DY.Helicobacter pylori: its epidemiology and its role in duodenal ulcer disease. J Gastroenterol Hepatol 1991; 6: 105–13.CrossRefGoogle ScholarPubMed
6.Morris, A, Nicholson, G, Lloyd, G, Haines, D, Rogas, A, Taylor, D. Seroepidemiology of Campylobacter pyloridis. N Z Med J 1986; 89: 657–9.Google Scholar
7.Vaira, D, D'Anastasio, C, Holton, J et al. , Campylobacter pylori in abattoir workers: Is it a zoonosis? Lancet 1988; ii: 725–6.CrossRefGoogle Scholar
8.Jones, DM, Curry, A. Ultrastructural study of gastric Campylobacter-like organisms (GCLO) from man, pig and ferret. In: Kaijser, B, Falsen, E eds. Campylobacter VI, Gothenburg: University of Gothenburg, 1988; 109.Google Scholar
9.Newell, DG, Johnston, BJ, Ali, MH, Reed, PI. An enzyme-linked immunosorbent assay for the serodiagnosis of Campylobacter pylori-associated gastritis. Scan J Gastroenterol 1988; 23 (suppl 142): 53–7.CrossRefGoogle Scholar
10.Talley, NJ, Newell, DG, Ormand, JE et al. , Serodiagnosis of Helicobacter pylori: a comparison of enzyme-linked immunosorbent assays. J Clin Microbiol 1991; 29: 1635–9.CrossRefGoogle ScholarPubMed
11.Newell, DG. Human serum antibody responses to the surface proteins of Campylobacter pyloridis. Serodiagn Immunother 1987; 1: 209–17.CrossRefGoogle Scholar
12.Newell, DG, Rathbone, BJ. The serodiagnosis of Campylobacter pylori infection. Serodiagn Immunother 1989; 3: 1–6.CrossRefGoogle Scholar
13.Newell, DG, Hudson, MJ, Baskerville, A. Isolation of the stomach of four Rhesus monkeys and identification as Campylobacter pylori. J Med Microbiol 1988; 27: 41–4.CrossRefGoogle ScholarPubMed