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Somatic and “X” agglutinins to the Salmonella group

Published online by Cambridge University Press:  15 May 2009

J. C. Cruickshank
J. C. Cruickshank
Affiliation:
From the London School of Hygiene and Tropical Medicine
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An examination was made of 200 Wassermann sera, thirty-eight sera from typhoid, twenty-five from paratyphoid B and thirty-one from tuberculous cases, for somatic agglutinins to a range of Salmonellas representative of the O groups then available.

In the Wassermann sera O agglutinins, except to Bact. typhosum and Bact. paratyphosum B, were rare, and the titres against these organisms were low, attaining a titre of 1: 80 against Bact. typhosum in one serum only.

The sera of the enteric cases mostly possessed agglutinins to both Bact. typhosum O and Bact. paratyphosum B O. Cross-relations with Bact. paratyphosum A, Bact. london and, to a less extent, Bact. paratyphosum C, were common in the typhoid sera. Otherwise there was no evidence of relation amongst the somatic groups tested.

The response to T.A.B. inoculation of fifteen individuals suggested also the relation of some organism in the vaccine to Bact. london and its probable lack of relation to the other somatic groups.

There was no evidence of increased frequency of Salmonella agglutinins in tuberculous cases.

The cross-relations of the Salmonellas was found to be due to the possession of minor antigenic components and not to possession of X antigen, which was absent from the suspensions used. X agglutinins were not more frequent in the pathological than in the Wassermann sera.

The relation of these findings to the diagnostic agglutination test is discussed, and the possibility of error consequent upon the use of suspensions containing X antigen is pointed out.

Type
Research Article
Information
Journal of Hygiene , Volume 39 , Issue 3 , May 1939 , pp. 224 - 237
Copyright
Copyright © Cambridge University Press 1939

References

REFERENCES

Alves, W. D. (1936). S. Afr. med. J. 10, 7.Google Scholar
Damon, S.R. (1937). Amer. J. Hyg. 26, 40.Google Scholar
Dowdeswell, R. M. (1937). Trans. R. Soc. trop. Med. Hyg. 31, 363.CrossRefGoogle Scholar
Downie, A. W. & Fairbrother, R. W. (1934). Brit. Med. J. p. 55.CrossRefGoogle Scholar
Felix, A. (1924). J. Immunol. 9, 115.CrossRefGoogle Scholar
Felix, A. (1930). Lancet, 1, 505.CrossRefGoogle Scholar
Felix, A. & Gardner, A.D. (1937). Bull. Hlth Org. (League of Nations), 6, 223.Google Scholar
Gardner, A. D. & Stubington, E. F. (1932). J. Hyg., Camb., 32, 516.Google Scholar
Giglioli, G. (1933). J. Hyg., Camb., 33, 379.CrossRefGoogle Scholar
Gregory, T. C & Atkinson, Nancy (1938). J. Hyg., Camb., 38, 566.Google Scholar
Happold, F. C. (1928). J. Path. Bact. 31, 237.CrossRefGoogle Scholar
Happold, F. C. (1929). Brit. J. exp. Path. 10, 263.Google Scholar
Horgan, E. S. (1932). J. Hyg., Camb., 32, 523.Google Scholar
Kauffmann, F. (1937). Z. Hyg. InfektKr. 120, 177.CrossRefGoogle Scholar
Lewin, W. (1934). S. Afr. med. J. 8, 731.Google Scholar
Madgwick, J. R. A. & Partner, F. (1932). Lancet, 1, 1091.CrossRefGoogle Scholar
Martin, P. H. (1933). Ann. Rep. Inst. med. Res. F.M.S. p. 14.Google Scholar
Smith, J. (1932). J. Hyg., Camb., 32, 143.Google Scholar
Topley, W. W. C. & Ayrton, J. (1924). J. Hyg., Camb., 23, 198.Google Scholar
White, P. B. (1926). Spec. Rep. Ser. med. Res. Coun., Lond., no. 103.Google Scholar
Wyllie, J. (1937). J. Hyg., Camb., 37, 70.CrossRefGoogle Scholar