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Transferable resistance to trimethoprim in enteric pathogens isolated in Kuwait

Published online by Cambridge University Press:  19 October 2009

T. D. Chugh
T. D. Chugh
Affiliation:
Faculty of Medicine, University of Kuwait, P.O. Box 24923, Kuwait
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Trimethoprim resistance was seen in 14·8% of 500 strains of salmonella, 43·1% of 153 strains ofshigella and 59% of 27 strains of Escherichia coli isolated from stools of patients with diarrhoea. Strains with a high level of trimethoprim resistance (MIC of ≥ 512 μg) were subjected to conjugal transfer. Trimethoprim resistance was plasmid-mediated in all of 42 strains of shigella and 12 strains of E. coli examined. However, 2 of the 47 strains of salmonella could not transfer their trimethoprim resistance either directly or by mobilization with the transfer factors X and Δ both at 37 and 25 °C overnight incubation.

Type
Research Article
Information
Journal of Hygiene , Volume 95 , Issue 2 , October 1985 , pp. 391 - 395
Copyright
Copyright © Cambridge University Press 1985

References

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