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A pharmacokinetic-dynamic explanation of the rapid onset–offset of rapacuronium
Published online by Cambridge University Press: 16 August 2006
Abstract
The rapid onset and offset of rapacuronium can be explained from its pharmacokinetic and pharmacodynamic characteristics. A unique property of rapacuronium is its high value for ke0, indicating a rapid access to the receptor site. The reason for this high ke0 may be related to the low intrinsic potency of rapacuronium, but this is not yet fully clarified.
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- 2001 European Society of Anaesthesiology
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