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Síntomas depresivos durante el mantenimiento con buprenorfina frente a metadona: hallazgos de un ensayo controlado distribuido al azar en la dependencia de opioides

Published online by Cambridge University Press:  12 May 2020

Angela J. Dean ,
James Bell ,
Macdonald J. Christie  and
Richard P. Mattick
Angela J. Dean
Affiliation:
Departamento de Psiquiatría, Universidad de Queensland 4029, Australia. The Langton Centre, Nobbs St., Surry Hills 2010, Australia. Departamento de Farmacología y Fundación Médica, Universidad deSidney2006, Australia.
James Bell
Affiliation:
The Langton Centre, Nobbs St., Surry Hills 2010, Australia.
Macdonald J. Christie
Affiliation:
Departamento de Farmacología y Fundación Médica, Universidad deSidney2006, Australia.
Richard P. Mattick
Affiliation:
Centro Nacional de Investigación en Drogas y Alcohol, Universidad de Nueva Gales del Sur, 2052, Australia.
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Resumen

La investigación indica que la buprenorfina puede poseer actividad antidepresiva. Sujetos dependientes de la heroina que recíbian mantenimiento de buprenorfina o metadona como parte de un ensayo doble ciego preexistente mayor realizado por el NDARC (Australia) rellenaron el Inventario de Depresión de Beck en la línea de base y a los tres meses. Los síntomas depresivos mejoraron en todos los sujetos, sin diferencia entre los grupos de metadona y buprenorfina, indicando que no había beneficio diferencial en los síntomas depresivos para la buprenorfina comparado con la metadona.

Keywords

BuprenorfinaAntidepresivoDepresiónDependencia de opioidesMetadona
Type
Comunicación breve
Information
European Psychiatry (Ed. Española) , Volume 12 , Issue 3 , April 2005 , pp. 185 - 191
Copyright
Copyright © European Psychiatric Association 2005

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Footnotes

Dean AJ, Bell J, Christie MJ, Mattick RP. Depressive symptoms during buprenorphine vs. methadone maintenance: findings from a randomised, controlled trial in opioid dependence. Eur Psychiatry 2004;19:510-513.

References

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