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Depresión y Ansiedad como un Trastorno único: Datos de Potenciales Evocados Auditivos del Tallo Cerebral

Published online by Cambridge University Press:  12 May 2020

R. Kimhi ,
Y. Barak ,
D. Levy  and
A. Elizur
R. Kimhi
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
Y. Barak
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
D. Levy
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
A. Elizur
Affiliation:
Centro de Salud Mental Y Abarbanel, 15 Keren Kaymet, St., Bat-Yam59100, Israel
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Resumen

La ansiedad y la depresión están entrelazadas a menudo, como demuestran los estudios clínicos, epidemiológicos, psicofarmacológicos e incluso genéticos. Sin embargo, son escasos los datos bioquímicos y electrofisiológicos sólidos de la unión o separación de los trastornos del estado de ánimo y de ansiedad. Los potenciales evocados auditivos del tallo cerebral (BSAEPs) se pueden medir de manera sencilla y no invasiva en los pacientes psiquiátricos y reflejan procesos neurofisiológicos en este lugar del cerebro. El propósito del presente estudio era evaluar los BSAEPs en pacientes que sufrían trastorno de pánico o depresión mayor y no tomaban medicación y compararlos con controles sanos. Se diagnosticó a los pacientes (n = 26; pánico = 16, depresión = 10) según los criterios del Manual Diagnóstico y Estadístico (DSM) III-R evaluados por las Escalas de Valoración de Hamilton para la Ansiedad y para la Depresión, y todos pasaron por un período de limpieza del organismo de las medicaciones de 3 semanas. Todos los sujetos (n = 36) completaron el estudio. La latencia del componente N3 disminuyó en el grupo de pacientes (P < 0,05), el intervalo N3-5 se alargó (P < 0,05), la latencia del componente N3 correlacionó con las puntuaciones de ansiedad y las puntuaciones de depresión correlacionaron con los períodos de latencia de los componentes N3 y N5. En conclusión, la pequeña muestra que utilizamos demostró la presencia de variables electrofisiológicas compartidas en el trastorno de pánico y la depresión, lo que da nuevo apoyo al concepto de trastorno de espectro.

Keywords

potenciales evocados tempranospotenciales evocados auditivos del tallo cerebraltrastorno de pánicodepresión mayorespectro afectivo
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 5 , Issue 5 , June 1998 , pp. 294 - 301
Copyright
Copyright © European Psychiatric Association 1998

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References

BIBLIOGRAFIA

Agren, H. Depression and somatosensory evoked potentials. Biol Psychiatry 1983; 18 (6): 635-49.Google ScholarPubMed
Cadet, JL. Disorders of the isodendretic core of the brainstem. Schiz Bulletin 1984; 1: 1–3.Google Scholar
Crowe, RRNoyes, RPauls, DL. Slymen D. A family study of panic disorder. Arch Gen Psychiatry 1983; 40: 1065-9.CrossRefGoogle Scholar
American Psychiatric Institute (APA). Diagnostic and statistical manual of mental disorders. Washington DC, 1994.Google Scholar
Eaton, WWRitter, C. Distinguishing anxiety and depression with field survey data. Psychol Med 1988; 18: 155-66.CrossRefGoogle ScholarPubMed
Gurney, CRoth, MGarside, RFKere, TASchapira, K. Studies in the classification of affective disorders. The relationship between anxiety States and depressive illness. Br J Psychiatry 1972; 121: 162-6.CrossRefGoogle Scholar
Hamilton, M. The assessment of anxiety States by rating. Brit J Med Psychology 1959; 32: 50-5.CrossRefGoogle ScholarPubMed
Hamilton, M. A rating scale for depression. JNNP 1960; 23: 55–62.Google ScholarPubMed
Harell, MEnglender, MKimhi, RDemer, M. Zohar M. Auditory brain stem responses in schizophrenic patients. Larynscope 1986; 96: 908-10.CrossRefGoogle Scholar
Harris, JC. Experimental animal modelling of depression and anxiety. Psychiatr Clin NorthAm 1989; 2: 815-21.CrossRefGoogle Scholar
Hoehn-Soric, RMerchant, AFKeyser, ML. Effects of clonidine on anxiety disorders. Arch Gen Psychiatry 1981; 38: 1278-82.CrossRefGoogle Scholar
Jacob, RGMoller, MBTumer, SM. Otoneurological examination in panic disorder and agoraphobia with panic attacks: a pilot study. Am J Psychiatry 1985; 142 (6): 715-20.Google ScholarPubMed
Kimhi, RLevy, DZohar, MAchiron, AElizur, A, Depression and schizophrenia -brain stem auditory evoked potentials. Eur Neuropsychopharmacol 1996; 6 (suppl): 51-3.CrossRefGoogle Scholar
Klerman, GL. Anxiety and depression. In: Burrows, GD, ed. Handbook of Studies on Depression. New York: Excepta Medica, 1977.Google Scholar
Knott, VJLapierre, YD. Effects of lactate induced panic attaks on BSAER Neuropsychobiology 1986; 16: 714-18.CrossRefGoogle Scholar
Kraemer, GWEbert, MHSchmidt, DE. McKinney, WT. Strangers in a strange land: A psychobiological study of infant monkeys before and after separation from real or inmate mothers. Child Dev 1991; 62: 548-59.CrossRefGoogle Scholar
Lapierre, YDHamilton, DM. Anxiety and depression: distinct or continuum. Focus Depress Anxiety 1993; 4 (4): 76–81.Google Scholar
Lebowitz, MRGorman, JMFyer, A. Possible mechanisms for lactate induction of panic. Am J Psychiatry 1986; 143: 495–502.Google Scholar
Leckman, JFWeissman, MMMerikangas, KR. Panic disorder and major depression. Increased risk of depression, alcoholism, panic disorder in families of depressed probands with panic disorder. Arch Gen Psychiatry 1983; 40: 1055-60.CrossRefGoogle ScholarPubMed
Mapother, E. Discussion on manic-depressive psychosis. BMJ 1926: 872-86.Google Scholar
Montgomery, SA. Anxiety and depresssion. In. Anxiety and Depression. Montgomery, SA, ed. Petersfield, Hampshire: Wrightson Biomedical Publishing Ltd, 1990: 1–8.Google Scholar
Mountjoy, CQRoth, M. Studies in the relationship between depressive disorders and anxiety States. J Affective Dis 1982; 4: 149-61.CrossRefGoogle ScholarPubMed
Picton, TWStuss, DTChampagne, SC. Nelson, RF. The effects of age on human event-related potentials. Psychophysiology 1984; 21: 312-25.Google ScholarPubMed
Pfefferbaum, AWenegrat, BFord, JRoth, WT. Kopell, BS. Clinical application of the P3 component of eventrelated potentials, II: dementia, depression and schizophrenia. Electrocephalogr Clin Neurophysiol 1984; 59: 104-24.CrossRefGoogle Scholar
Pfefferbaum, ARoth, WTFord, JM. Event-related potentials in the study of psychiatric disorders. Arch Gen Psychiatry 1995; 52: 559-63.CrossRefGoogle Scholar
Rappapot, MMcCandless, KLPond, W. Krafft, MC. Pasive P300 response in traumatic brain injury patients. J Neuropsychiatry Clin Neurosci 1991; 3 (2): 180-5.Google Scholar
Shagass, C. An electrophysiological view of schizophrenia. Biol Psychiatry 1976; 11: 3–30.Google ScholarPubMed
Shagass, C. Early evoked potentials. Schiz Bull 1977; 3: 80–92.CrossRefGoogle ScholarPubMed
Vanvalkenburg, CAkiskal, HSPuzantian, V. Rosenthal T. Anxiety depression. Clinical family history and naturalistic outcome. J Affect Dis 1984; 6: 67–82.Google Scholar
Vollrath, MKoch, RAngst, J. The Zurich study. Panic disorder and sporadic panic: Symptoms, diagnosis, prevalence and overlap with depression. Eur Arch Psych Neur Sciences. 1990; 239: 221-30.CrossRefGoogle ScholarPubMed