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Effect of tianeptine on the hypothalamic control of the corticotropic response to stress
Published online by Cambridge University Press: 16 April 2020
Summary
Stress-induced stimulation of corticotropic function involves the activation of hypothalamic corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP), which can be measured by improved methods of neuroendocrine investigation. The antiserotoninergic tricyclic antidepressant, tianeptine, reduces the corticotropic response to stress, as shown by a reduction in hypothalamo-hypophyseal portal CRH and AVP levels.
Keywords
- Type
- Research Article
- Information
- European Psychiatry , Volume 8 , Issue S2: Neuroendocrinological aspects of depression 28 June 1992, Nice, France , 1993 , pp. 55s - 60s
- Copyright
- Copyright © Elsevier, Paris 1993
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