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Importance of the type of pharmacological treatment in patients with severe mental disorder

Published online by Cambridge University Press:  27 August 2024

M. Lucas
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
P. Romero*
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
N. Sirvent
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
R. Roig
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
J. Bajén
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
M. Aliño
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
C. Escobar
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
C. López
Affiliation:
PSYCHIATRIC, SESCAM, ALBACETE, Spain
*
*Corresponding author.

Abstract

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Introduction

The use of long-acting treatments is a common clinical practice in psychiatry. No disease insight and the risk of treatment discontinuation in a significant portion of our patients, increase the demand for psychiatric emergency and hospital admissions. Treatment adherence must be facilitated, taking into account possible side effects and patient´s subjective satisfaction.

Objectives

-Evaluate the type of long-acting intramuscular treatment in selected patients. -Evaluate the differences in treatment satisfaction between different types of long-acting intramuscular treatments as well as frequency of psychiatric emergency and hospital admissions in the last year.

Methods

We select patients with different severe mental disorders who stay in a Medium Stay Unit, Sociosanitary Community Residence, Supervise house and Residence for the elderly in Albacete (Spain); all of them, with intramuscular neuroleptic treatment (zuclopenthixol dihydrochloride, aripiprazole long acting, palmitate paliperidone monthly, 3-monthly and 6-monthly) at least 1 year.

We evaluate their sociodemographic characteristics, the satisfaction questionnaire with the treatment (TSQM-9) and the rate of psychiatric emergencies and admissions after current intramuscular treatment in last year.

Results

We have selected 57 patients with an average age of 45.86. 78.94% with a diagnosis of schizophrenia, 12.28% with schizoaffective disorder, 5.26% bipolar disorder and 3.5% unspecified psychotic disorder.

We can see in the graphics below that the longer duration of the intramuscular treatment, the greater satisfaction in all the items of the TSQM-9 questionnaire.

31% of the patients with zuclopenthixol dihydrochloride treatment, have gone to psychiatric emergencies and 28% of psychiatric admissions in the last year.18% of the patients with aripiprazole long acting, 17% with paliperidone palmitate long acting-monthly and 12% de 3-monthly have gone to psychiatric emergencies and 15%, 12% and 12% needed psychiatric admissions respectively. Patients with palmitate long acting-monthly have not emergencies or psychiatric admissions in the last year.

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Conclusions

  • - The longer long acting of the intramuscular treatments, the better patient satisfaction.

  • - With the longer duration treatment (Palmitate paliperidone LD 6 month), we have lower psychiatric emergencies and hospital admissions.

Disclosure of Interest

None Declared

Type
Abstract
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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