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Low-dose neuroleptic therapy and extrapyramidal side effects in schizophrenia: an effect size analysis
Published online by Cambridge University Press: 16 April 2020
Summary
A meta-analysis of the published literature was performed in order to quantify the efficacy of low-dose neuroleptic therapy in reducing extrapyramidal side effects in schizophrenic patients. A low-dose regimen between 50–100 mg equivalents of chlorpromazine, in comparison to a standard-dose regimen between 200–500 mg reduced extrapyramidal side effects by a 0.30 (±0.12) standard deviation, which is only a limited effect.
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- Copyright © Elsevier, Paris 1996
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