Lacunar infarcts are often considered benign as they do not usually cause clinically significant neurological/neuropsychiatric deficits. In this presentation, we highlight the case of a middle aged female who develop psychiatric symptoms from lacunar infarcts in the corona Radiata; necessitating in pharmacological intervention. The possible association of Lacunar infarct in Corona Radiata with neuropsychiatric symptoms may help in dealing with these patients with psychiatric symptoms, more effectively.