This workshop will focus on diagnostic and clinical issues in the treatment of Lesbian, Gay, Bisexual, and Transgender (LGBT) patients. Dr. Carrion, a Puerto Rican will speak on the role of coping, social support, temperament and subjective stress on posttraumatic symptoms, using “Coming-Out” or integration of a LGBT sexual orientation. He will discuss findings from a cohort of children who have experienced interpersonal violence and develop posttraumatic symptoms. Temperament will be discussed as a potential mediator and coping style as a moderator of posttraumatic symptoms. Dr. Garza, a Mexican American will describe concepts of gender identity and gender roles, and what role psychiatry has played in this area and how it may become a source of support for individuals struggling with gender dysphoria. Dr. Navarro-Barrios from Granada, Spain will speak about transcultural psychiatry and immigrant gay men. Transcultural psychiatry emphasizes the relation that exists between the culture of the subject, and the different presentation of the mental pathology. He will emphasizes the application of transcultural model in therapy with the immigrant gay subjects. Dr. Nakajima, a Japanese American will discuss problematic diagnoses related to homosexuality in ICD-10 like ego dystonic sexual orientation, and the drive to eliminate these diagnoses in ICD-11.