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Vortioxetine as an effective drug in the treatment of depression in adolescents with long QT index. A case report

Published online by Cambridge University Press:  27 August 2024

P. Del Sol Calderon ,
A. Izquierdo de la Puente ,
R. Fernández  and
M. García Moreno
P. Del Sol Calderon*
Affiliation:
1Psychiatry, Hospital Puerta de Hierro
A. Izquierdo de la Puente
Affiliation:
1Psychiatry, Hospital Puerta de Hierro
R. Fernández
Affiliation:
2Psychiatry, Hospital Universitario Infanta Cristina, Madrid, Spain
M. García Moreno
Affiliation:
1Psychiatry, Hospital Puerta de Hierro
*
*Corresponding author.

Abstract

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Introduction

This is a 13-year-old female patient admitted to the psychiatric unit active suicidal ideation.

Objectives

the objective is to show through a clinical case how vortioxetine can be safe in adolescents.

Methods

Case report and literature review

Results

She has a history of daily consumption of at least 2 units of cannabis per day. She presents high emotional distress secondary to academic failure, consuming the substance as a coping strategy. Due to prohibition and control by her parents, the patient stopped taking the substance, presenting severe depressive symptoms, self-injury and suicide ideation. For this reason she is admitted to the inpatient psychiatric unit. The electrocardiogram performed on admission shows a corrected QT index of 524. Exploring physical symptoms, she recognized episodes of syncope and palpitations. Coordination was made with cardiology, who performed an echocardiogram with normal results and began follow-up with them without prescribing medication. It was agreed not to use drugs that could prolong the QT index. Evaluating the clinical situation, it was decided to start treatment with Vortioxetine up to 10 mg. With this treatment there was no worsening of the electrocardiogram and the patient’s mood improved, anxiety and ideas of death were remitted

Conclusions

This work aims to show how vortioxetine has been effective and safe at the cardiological level in the case of moderate-severe depression in an adolescent with prolonged QT index

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S454 - S455
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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