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PROTEOMICS APPROACHES IN PRE-ECLAMPSIA RESEARCH

Part of: Bespoke shallow archive Weizmann

Published online by Cambridge University Press:  01 May 2009

OLIVIA CLANCY  and
JENNY E. MYERS
OLIVIA CLANCY
Affiliation:
Maternal and Fetal Health Research Centre, St Mary's Hospital, The University of Manchester, Manchester.
JENNY E. MYERS*
Affiliation:
Maternal and Fetal Health Research Centre, St Mary's Hospital, The University of Manchester, Manchester.
*
Dr Jenny Myers, Maternal and Fetal Health Research Centre, University of Manchester, St Mary's Hospital, Hathersage Rd, Manchester, M13 0JH, United Kingdom.
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Extract

Much of our current understanding of human gestation is largely based on information extracted from animal and cell models. Although this information has been fundamental for progression of reproductive research, much of it examines biological molecules in isolation rather than the integrated manner in which they function. Disruption to these fundamental processes is the source of pregnancy complications, of which for many (including pre-eclampsia) the exact aetiology has not been fully elucidated. We need to re-examine the limited way by which we approach these problems, and aim to understand pathophysiology in a more inclusive/holistic way.

Type
Research Article
Information
Fetal and Maternal Medicine Review , Volume 20 , Issue 2 , May 2009 , pp. 143 - 160
Copyright
Copyright © Cambridge University Press 2009

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