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CHOICE AND ROUTE OF OPIOIDS FOR ANALGESIA DURING LABOUR

Published online by Cambridge University Press:  15 December 2005

DONALD H PENNING
Affiliation:
John Hopkins University School of Medicine, Baltimore

Extract

Reports in the 1970's by Snyder and others of opioid receptors in the brain and the substantia gelatinosa of the spinal cord triggered a search for endogenous opioid ligands (β-endorphin and the encephalin peptides) which might modify pain transmission. It was not long after that morphine was administered into the human epidural space for pain control, including obstetric patients.

Type
Research Article
Copyright
© 2005 Cambridge University Press

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