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The characterization of an alanine racemase mutant of Escherichia coli

Published online by Cambridge University Press:  14 April 2009

H. J. W. Wijsman
H. J. W. Wijsman
Affiliation:
Institute of Genetics, University of Amsterdam, Amsterdam, the Netherlands

Summary

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Among temperature-sensitive mutants of Escherichia coli a strain was discovered requiring D-alanine for growth. It was proved to possess an altered alanine racemase. The structural gene for this enzyme, designated alr, is located between metB and pur A. The properties of the enzyme and its locus suggest that it is not under control of the mechanisms which regulate mucopeptide formation. A suppressor of the alr mutation was discovered near trp, and termed msuA.

Type
Research Article
Information
Genetics Research , Volume 20 , Issue 3 , December 1972 , pp. 269 - 277
Copyright
Copyright © Cambridge University Press 1972

References

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