Hostname: page-component-5c6d5d7d68-7tdvq Total loading time: 0 Render date: 2024-08-08T11:24:09.604Z Has data issue: false hasContentIssue false

The extent of rII deletions in phage T4

Published online by Cambridge University Press:  14 April 2009

William F. Dove
Affiliation:
Medical Research Council Unit for Molecular Biology, Hills Road, Cambridge, England

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The extent of certain rII deletions in phage T4 has been mapped by genetic means beyond the terminus of the B cistron. They extend to varying degrees, nearly to the acs locus. The phenotypes of these mutants indicate that there are two or three cistrons between rII B and acs, and that the functions coded for by these cistrons are not essential for growth in any known E. coli K12 strain or E. coli lysogen.

Type
Short Papers
Copyright
Copyright © Cambridge University Press 1968

References

REFERENCES

Bautz, F. A. & Bautz, E. K. F. (1967). Mapping of deletions in a non-essential region of the phage T4 genome. J. molec. Biol. 28, 345356.Google Scholar
Benzer, S. (1955). Fine structure of a genetic region in bacteriophage. Proc. natn. Acad. Sci. U.S.A. 41, 344354.Google Scholar
Benzer, S. (1961). On the topography of the genetic fine structure. Proc. natn. Acad. Sci. U.S.A. 47, 403415.Google Scholar
Bode, W. (1963). Zur natur der ausgedehnten Mutationen des Coliphagen T4. Z. Vererbungs-lehre, 94, 190199.Google Scholar
Edgar, R. S. & Epstein, R. H. (1961). Inactivation by ultraviolet light of an acriflavine-sensitive gene function in phage T4D. Science, N.Y. 134, 327328.Google Scholar
Edgar, R. S., Feynman, R. P., Klein, S., Lielausis, I. & Steinberg, C. M. (1962). Mapping experiments with r mutants of bacteriophage T4D. Genetics 47, 179186.Google Scholar
Edgar, R. S. & Lielausis, I. (1965). Serological studies with mutants of phage T4D defective in genes determining tail fiber structure. Genetics 52, 11871200.CrossRefGoogle ScholarPubMed
Sechaud, J., Streisinger, G., Emrich, J., Newton, J., Lanford, H., Reinhold, H. & Stahi, M. M. (1965). Chromosome structure in phage T4, II. Terminal redundancy and heterozygosis. Proc. natn. Acad. Sci. U.S.A. 54, 13331339.Google Scholar
Silver, S. (1965). Acriflavine resistance: a bacteriophage mutation affecting the uptake of dye by the infected bacterial cells. Proc. natn. Acad. Sci. U.S.A. 53, 2430.CrossRefGoogle ScholarPubMed
Stahl, F. W., Edgar, R. S. & Steinberg, J. (1964). The linkage map of bacteriophage T4. Genetics 50, 539552.CrossRefGoogle ScholarPubMed
Tessman, I. (1962). The induction of large deletions by nitrous acid. J. molec. Biol. 5, 442445.CrossRefGoogle ScholarPubMed