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Heritability of cranium bifidum and spina bifida in the golden hamster

Published online by Cambridge University Press:  14 April 2009

A. M. Moffa  and
J. A. White
A. M. Moffa
Affiliation:
Department of Biology, West Virginia University, Morgantown W. Va. 26506, U.S.A.
J. A. White
Affiliation:
Box 1284, West Virginia University Medical School

Summary

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The heritability (h2) and frequency of the neural tube closure defects, cranium bifidum (CB) and spina bifida (SB), have been estimated for a population of 9-day-old hamster embryos through half-sibling analysis. The average frequency of the total affected embryos per litter is approximately 17% while the pooled estimate for h2 based on between sires and between dams within sires components was 4%. This value points to the importance of environmental factors in contributing to the variance in defect frequencies observed within this population.

Type
Short papers
Information
Genetics Research , Volume 34 , Issue 2 , October 1979 , pp. 189 - 194
Copyright
Copyright © Cambridge University Press 1979

References

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