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Polymorphism of lactate dehydrogenase B subunit in rat erythrocytes

Published online by Cambridge University Press:  14 April 2009

V. Stolc
V. Stolc
Affiliation:
Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15261

Summary

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Lactate dehydrogenase regulator gene Ldr-1 controls the amount of the lactate dehydrogenase A subunit in rat serum and the amount of lactate dehydrogenase B subunit in rat erythrocytes because no recombinant rats were found among 295 pups produced in the BDIV × (ACI × BDIV)F1 and (ACI × DI) Fl × DI backcrosses. Two alleles regulate the high (Ldr-1a) and low (Ldr-1b) activity enzyme. The Ldr-1 is not linked to hooded coat pattern or glyoxalase-1. Sex and Ldr-1 assorted independently; hence the gene is autosomal.

Type
Short Paper
Information
Genetics Research , Volume 45 , Issue 1 , February 1985 , pp. 101 - 106
Copyright
Copyright © Cambridge University Press 1985

References

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