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Population structure in artificial selection: studies with Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

F. E. Madalena  and
Alan Robertson
F. E. Madalena
Affiliation:
Institute of Animal Genetics, West Mains Road, Edinburgh EH9 3JN, Scotland
Alan Robertson
Affiliation:
Institute of Animal Genetics, West Mains Road, Edinburgh EH9 3JN, Scotland

Summary

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The effect of sub-dividing a population during selection was studied by selecting downwards for sternopleural bristles in Drosophila melanogaster. The four structures used all involved the selection of 40 individuals out of 200 measured in each sex. The alternatives were:

(i) one large line with the same selection procedure in all generations,

(ii) eight small lines with the same procedure in all generations,

(iii) the ‘single cycle’ structure in which large lines derived from crosses between selected small lines at either the sixth or twelth generation, and,

(iv) the ‘repeated cycle’ structure in which the best five small lines were mixed at the sixth generation of selection to produce a new set of small lines on which the procedure was repeated for a total of three cycles.

Of the first two methods, the large line had a higher final response than did any of the small lines. The latter, selected with an intensity of 5 out of 25 in each sex, had lower average final response than had a similar group of lines selected from the same base population with the lower intensity of 10/25. The results showed no clear effect of the sub-dicision of the population, followed by selection between lines, though they were in general agreement with theortical expectations. Several second chromosome recessive lethals were found at high frequencies in different selected lines. One of these, found in eight of the lines, had an effect on bristles in the heterzygote of about 1·5 phenotypic standard deviations. The evidence strongly suggests a pleiotropic effect on bristle score.

Type
Research Article
Information
Genetics Research , Volume 24 , Issue 2 , October 1974 , pp. 113 - 126
Copyright
Copyright © Cambridge University Press 1974

References

REFERENCES

Clayton, G. A. & Robertson, A. (1957). An experimental check on quantitative genetical theory. II. Long term effects of selection. Journal of Genetics, 55, 131–151.CrossRefGoogle Scholar
Frankham, R., Jones, L. P. & Barker, J. S. F. (1968). The effects of population size and selection intensity in selection for a quantitative character. III. Analysis of the lines. Genetical Research 12, 267–283.CrossRefGoogle Scholar
Hill, W. G. (1963). M.Sc. thesis. University of California, Davis, Cal.Google Scholar
Hollingdale, B. (1971). Analyses of some genes from abdominal bristle number selection lines in Drosophila melanogaster. Theoretical and Applied Genetics 41, 292–301.CrossRefGoogle Scholar
Latter, B. D. H. (1966). The response to artificial selection due to autosomal genes of large effect. III. The effect of linkage on the rate of advance and approach to fixation in finite populations. Australian Journal of Biological Science 19, 131–146.CrossRefGoogle Scholar
Latter, B. D. H. & Robertson, A. (1962). The effects of inbreeding and artificial selection on reproductive fitness. Genetical Research 3, 110–138.CrossRefGoogle Scholar
Madalena, F. E. & Hill, W. G. (1972). Population structure in artificial selection programmes: simulation studies. Genetical Research 20, 75–101.CrossRefGoogle ScholarPubMed
Maruyama, T. (1970). On the fixation probability of mutant genes in a subdivided population. Genetical Research, 15, 221–225.CrossRefGoogle Scholar
McPhee, C. P. & Robertson, A. (1968). The effect of suppressing crossing-over on the response to selection in Drosophila melanogaster. Genetical Research, 16, 1–16.CrossRefGoogle Scholar
Osman, H. & Robertson, A. (1968). The introduction of genetic material from inferior into superior strains. Genetical Research 12, 221–236.CrossRefGoogle ScholarPubMed
Rathie, K. A. & Barker, J. S. F. (1968). Effectiveness of regular cycles of intermittent artificial selection for a quantitative character in Drosophila melanogaster. Australian Journal of Biological Science 21, 1187–1213.CrossRefGoogle ScholarPubMed
Robertson, A. (1960). A theory of limits in artificial selection. Proceedings of the Royal Society B 153, 234–249.Google Scholar
Robertson, F. W. & Reeve, E. C. R. (1952). Studies in quantitative inheritance. I. The effect of selection on wing and thorax length in Drosophila melanogaster. Journal of Genetics 50, 414–448.CrossRefGoogle Scholar
Wright, S. (1951). The genetic structure of populations. Annals of Eugenics 15, 323–354.CrossRefGoogle Scholar