Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-09T03:29:32.718Z Has data issue: false hasContentIssue false

Association between meeting core elements for inpatient antimicrobial stewardship and antibiotic utilization

Published online by Cambridge University Press:  24 June 2019

Shaina R. Bernard
Affiliation:
Division of Surveillance and Investigation, Virginia Department of Health, Richmond, Virginia
Kristi M. Kuper
Affiliation:
Vizient, Irving, Texas
Kimberly B. Lee
Affiliation:
Virginia Commonwealth University Health, Richmond, Virginia
Michael P. Stevens
Affiliation:
Department of Hospital Epidemiology and Infection Control, Virginia Commonwealth University, Richmond, Virginia
Samuel F. Hohmann
Affiliation:
Vizient, Irving, Texas Department of Health Systems Management, Rush University, Chicago, Illinois
Natalie Nguyen
Affiliation:
Virginia Commonwealth University Health, Richmond, Virginia
Amy L. Pakyz*
Affiliation:
Department of Pharmacotherapy and Outcomes Science, Virginia Commonwealth University Richmond, Virginia
*
Author for correspondence: Amy L. Pakyz, PhD, 410 North 12th Street, Box 980533, Richmond, VA, 23298, USA. Email: apakyz@vcu.edu

Abstract

We used multivariable analyses to assess whether meeting core elements was associated with antibiotic utilization. Compliance with 7 elements versus not doing so was associated with higher use of broad-spectrum agents for community-acquired infections [days of therapy per 1,000 patient days: 155 (39) vs 133 (29), P = .02] and anti-methicillin-resistant S. aureus agents [days of therapy per 1,000 patient days: 145 (37) vs 124 (30), P = .03].

Type
Concise Communication
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved. 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Core elements of hospital antibiotic stewardship programs: antibiotic use. Centers for Disease Control and Prevention website. https://www.cdc.gov/antibiotic-use/healthcare/implementation/core-elements.html. Published December 12, 2017. Accessed January 8, 2019.Google Scholar
Antimicrobial stewardship. Joint Commission website. http://www.jointcommission.org/topics/hai_antimicrobial_stewardship.aspx. Accessed January 8, 2019.Google Scholar
Moehring, RW, Anderson, DJ, Cochran, RL, et al. Expert consensus on metrics to assess the impact of patient-level antimicrobial stewardship interventions in acute-care settings. Clin Infect Dis 2017;64:377383.CrossRefGoogle ScholarPubMed
O’Leary, EN, van Santen, KL, Webb, AK, Pollock, DA, Edwards, JR, Srinivasan, A. Uptake of antibiotic stewardship programs in US acute care hospitals: findings from the 2015 National Healthcare Safety Network Annual Hospital Survey. Clin Infect Dis 2017;65:17481750.CrossRefGoogle ScholarPubMed
van Santen, KL, Edwards, JR, Webb, AK, et al. The standardized antimicrobial administration ratio: a new metric for measuring and comparing antibiotic use. Clin Infect Dis 2018;67:179185.CrossRefGoogle ScholarPubMed
Patterson, JA, Edmond, MB, Hohmann, SF, Pakyz, AL. Association between high-risk medication usage and healthcare facility-onset C. difficile infection. Infect Control Hosp Epidemiol 2016;37:909915.CrossRefGoogle ScholarPubMed
Pakyz, AL, Moczygemba, LR, Wang, H, Stevens, MP, Edmond, MB. An evaluation of the association between an antimicrobial stewardship score and antimicrobial usage. J Antimicrob Chemother 2015;70:15881591.Google ScholarPubMed