Hostname: page-component-7bb8b95d7b-w7rtg Total loading time: 0 Render date: 2024-09-18T17:20:57.780Z Has data issue: false hasContentIssue false
  • English
  • Français

Infection Control: Opportunistic Fungal Infections—The Increasing Importance of Candida Species

Published online by Cambridge University Press:  21 June 2016

Michael A. Pfaller
Michael A. Pfaller*
Affiliation:
Veterans Administration Medical Center and the Department of Pathology, University of Iowa College of Medicine, Iowa City, Iowa
*
273 MRC, University of Iowa Hospitals and Clinics, Iowa City, IA 52242
Get access Rights & Permissions [Opens in a new window]

Extract

Opportunistic fungal infections increasingly are becoming important causes of morbidity and mortality in the hospitalized patient. In addition to the well-known pathogenic fungi such as the Zygomycetes and Aspergillus spp, serious infections are being reported with increasing frequency due to Fusarium spp, dematiacious fungi and other usually “nonpathogenic” fungi. Recent data, however, suggest that Candida spp are emerging as one of the major nosocomial pathogens in both seriously ill immunocompetent and immunocompromised patients. Given the importance of Candida spp as opportunistic fungal pathogens, this summary will focus on newer clinical and epidemiologic observations of nosocomial candidiasis.

Type
Program Summaries
Information
Infection Control & Hospital Epidemiology , Volume 10 , Issue 6 , June 1989 , pp. 270 - 273
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Richardson, SE, Bannatyne, RM, Summerbell, RC. et al: Disseminated fusarial infection in the immunocompromised host. Rev Infect Dis 1988;10: 1171–1181.Google Scholar
2. Pitrak, DL, Koneman, EL, Estupinan, RC. et al: Phialophora richardsiae infection in humans. Rev Infect Dis 1988; 10: 1195–1203.Google Scholar
3. Haron, E, Anaissie, F, Dumphy, F, et al: Hansenula anomala fungemia. Rev Infect Dis 1988: 10: 1182–1186.Google Scholar
4. Harvey, RI, Myers, JP: Nosocomial fungemia in a large community teaching hospital. Arch Intern Med 1987: 147: 2117–2120.Google Scholar
5. Horn, R, Wong, B, Kiehn, TE, et al: Fungemia in a cancer hospital: Changing frequency, earlier onset, and results of therapy. Rev Infect Dis 1985: 7: 640–655.CrossRefGoogle Scholar
6. Horan, T, Culver, D, Jarvis, W. et al: Pathogens causing nosocomial infections: Preliminary data from the National Nosocomial Infections Surveillance system. Antimicrobic Newsletter 1988; 5: 65–07.Google Scholar
7. Maksymiuk, AW, Throngprosert, S, Hopfer, R. et al: Systemic candidiasis in cancer patients. Am J Med 1984: 77: 20–27.Google Scholar
8. Wey, SB. Mori, M, Pfaller, MA. et al: Hospital-acquired candidemia: The attributable mortality and excess length of stay. Arch Intern Med 1988; 148: 2642–2645.Google Scholar
9. Martin, MA, Pfaller, MA, Wenzel, RP: Coagulase-negative staphylococcal bacteremia: Mortality and hospital stay. Ann Intern Med 1989; 110: 9–16.CrossRefGoogle ScholarPubMed
10. Miller, PJ, Wenzel, RP: Etiologie organisms as independent predictors ot death and morbidity associated with bloodstream infections. J Infect Dis 1987; 156: 471–477.Google Scholar
11. Schwartz, RS, Mackintosh, FR, Schrier, SL. et al: Multivariate analysis of factors associated with invasive fungal disease during remission-induction therapy for acute myelogenous leukemia. Cancer 1984; 53: 411–419.Google Scholar
12. Karabinis, A. Hill, C, Leclereq, B. et al: Risk factors for candidemia in cancer patients: A case-control study. J Clin Microbiol 1988; 20: 429–432.Google Scholar
13. Wey, SB. Mori, M, Pfaller, MA. et al: Risk factors for hospital acquired candidemia: A matched case-control study. Arch Intern Med 1989, in press.Google Scholar
14. Pfaller, MA: Strain variation among Candida species: Application of various typing methods to study the epidemiology and pathogenesis of candidiasis in hospitalized patients. Infect Cont 1987; 8: 273–276.Google Scholar
15. Burnie, JP. Matthews, R. Lee, W. et al: Fout outbreaks of nosocomial systemic candidiasis. Epidemiol Infect 1987; 99: 201–211.Google Scholar
16. Odds, FC: Biotyping of medically important fungi, in McGinnis, MR (ed): Current Topics in Medical Mycology, vol 1. New York, Springer-Verlag. 1985. pp 155–171.Google Scholar
17. Lee, W, Burnie, J, Matthews, R: Fingerprinting Candida albicans . J Immunol Methods 1986: 93: 177–182.Google Scholar
18. Odds, FC, Abbott, AB: A simple system for the presumptive identification of Candida albicans and differentiation of strains within the species. Sabouraudia 1980; 18: 301–317.Google Scholar
19. Polonelli, L, Archibusacci, C, Sestilo, M, et al: Killer system: A simple method for differentiating strains of Candida albicans . J Clin Microbiol 1983: 17: 771–780.Google Scholar
20. Scherer, S, Stevens, DA: Application of DNA typing methods to epidemiology and taxonomy of Candida species. J Clin Microbiol 1987; 25: 675–679.Google Scholar