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Nosocomial Fungal Infection During Hospital Renovation

Published online by Cambridge University Press:  02 January 2015

Keith Krasinski*
Affiliation:
Department of Pediatrics, Medicine, and Pathology, New York University Medical Center, Bellevue Hospital Center, New York, New York
Robert S. Holzman
Affiliation:
Department of Pediatrics, Medicine, and Pathology, New York University Medical Center, Bellevue Hospital Center, New York, New York
Bruce Hanna
Affiliation:
Department of Pediatrics, Medicine, and Pathology, New York University Medical Center, Bellevue Hospital Center, New York, New York
M. Alba Greco
Affiliation:
Department of Pediatrics, Medicine, and Pathology, New York University Medical Center, Bellevue Hospital Center, New York, New York
Michael Graff
Affiliation:
Department of Pediatrics, Medicine, and Pathology, New York University Medical Center, Bellevue Hospital Center, New York, New York
Madhu Bhogal
Affiliation:
Department of Pediatrics, Medicine, and Pathology, New York University Medical Center, Bellevue Hospital Center, New York, New York
*
Department of Pediatrics, New York University Medical Center, 550 First Avenue, New York, NY 10016

Abstract

Nosocomial fungal pulmonary infections (Zygomycetes, Aspergillus sp.) developed in two premature infants in a special care unit (SCU) adjacent to an area of renovation. Inspection showed that inadequate barriers permitted the passage of airborne particles between the two areas, and cultures confirmed a significantly higher (p≤0.05) density of mold spores in the SCU (0.88 cfu per hour per settling plate) compared to a construction-free comparison area (0.22 cfu per hour per settling plate). The major source of mold was the dust above the hospital's false ceiling. In another construction area, impervious barriers were shown to effectively restrict the dispersal of mold. Our experience adds Rhizopus to Aspergillus as a possible cause of construction-related nosocomial infection. Sporadic episodes will continue to occur until the hazards of renovation are appreciated and effective preventive measures are routinely instituted.

Type
Original Articles
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1985

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References

1.Diem, K, Lentner, C (eels): Documenta Geigy: Scientific Tables, ed 7. Basle Switzerland, JR Geigy SA, 1970.Google Scholar
2.Noble, WC, Clayton, YM: Fungi in the air of hospital wards. J Gen Microbiol 1963; 32:397402.CrossRefGoogle ScholarPubMed
3.Sayer, WJ, Shcan, DB, Ghosseiri, J: Estimation of airborne fungal flora by the Anderson sampler versus the gravity settling culture plate. Journal of Allergy 1969; 44:214227.Google Scholar
4.Kahanpaa, A: Bronchopulmonary occurrence of fungi in adults: Especially according to cultivation material. Acta Pathol Microbiol Immunol Scand 1972; Section B Suppl 227:1147.Google ScholarPubMed
5.Gage, AA, Dean, DC, Schimert, G, et al: Aspergillus infection after cardiac surgery. Arch Surg 1970; 101:384387.Google Scholar
6.Burton, JR, Zachery, JB, Bessin, R, et al: Aspergillosis in four renal transplant recipients. Diagnosis and effective treatment with amphotericin B. Ann Intern Med 1972; 77:383388.Google Scholar
7.Kyriakides, GK, Zinneman, HHA, Hall, WH, et al: Immunologic monitoring and aspergillosis in renal transplant patients. Am J Surg 1976; 131:246252.CrossRefGoogle ScholarPubMed
8.Rose, HD: Mechanical control of hospital ventilation and Aspergillus infections. Am Rev Respir Dis 1972; 105:306307.Google ScholarPubMed
9.Rosen, P, Steinberg, S: Decreased frequency of aspergillosis and mucormycosis (Letter to the Editor). N Engl J Med 1976; 295:1319.Google Scholar
10.Mahoney, DH, Steuber, CP, Starling, KA, et al: An outbreak of aspergillosis in children with acute leukemia. J Pediatr 1979; 95:7072.Google Scholar
11.Aisner, J, Schimpff, SC, Bennett, JE, et al: Aspergillus infections in cancer patients: Association with fireproofing materials in a new hospital. JAMA 1976; 235:411412.Google Scholar
12.Arnow, PM, Anderson, RL, Mainous, PD, et al: Pulmonary Aspergillosis during hospital renovation. Am Rev Respir Dis 1978; 118:4953.Google Scholar
13.Young, RC, Bennett, JE, Vogel, CL, et al: Aspergillus: The spectrum of disease in 98 patients. Medicine 1970; 49:147173.Google Scholar
14.Keys, TF, Haldorson, AM, Rhodes, KH, et al: Nosocomial outbreak of rhizopus infections associated with elastoplanl wound dressings. MMWR 1978; 27:33.Google Scholar
15.Dennis, JE, Rhodes, KH, Cooney, DR: Nosocomial Rhizopus infection (Zygomycosis) in children. J Pediatr 1980; 96:824828.Google Scholar
16.Krick, JA, Remington, JS: Opportunistic invasive fungal infections in patients with leukemia and lymphoma. Clin Haematol 1976; 5:249310.CrossRefGoogle Scholar
17.Ajello, L: A comparative study of pulmonary mycoses of Canada and the United States. Public Health Reports 1969; 84:869877.CrossRefGoogle ScholarPubMed
18.Hall, LB: Air sampling for hospitals. Hospital Topics 1962; 40:9798.CrossRefGoogle Scholar