Hostname: page-component-7bb8b95d7b-lvwk9 Total loading time: 0 Render date: 2024-09-13T03:59:53.906Z Has data issue: false hasContentIssue false
  • English
  • Français

Prevalence of and Risk Factors for Nasal Colonization With Staphylococcus aureus Among Human Immunodeficiency Virus-Positive Outpatients in Singapore

Published online by Cambridge University Press:  02 January 2015

J. S. Villacian ,
T. Barkham ,
A. Earnest  and
N. I. Paton
J. S. Villacian*
Affiliation:
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore
T. Barkham
Affiliation:
Department of Pathology and Laboratory Medicine, Tan Tock Seng Hospital, Singapore
A. Earnest
Affiliation:
Clinical Research Unit, Tan Tock Seng Hospital, Singapore
N. I. Paton
Affiliation:
Department of Infectious Diseases, Tan Tock Seng Hospital, Singapore
*
Department of Infectious Diseases, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore308433
Get access Rights & Permissions [Opens in a new window]

Abstract

We studied the prevalence of and risk factors for Staphylococcus aureus nasal colonization in HIV-positive outpatients in Singapore. Overall prevalence was 23% (45 of 195), with 3% (6 of 195) being MRSA. Recent antibiotic use and hospitalization were independent predictors of MRSA colonization. Isolates were genotypically identical to our hospital's inpatient circulating strain.

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 25 , Issue 5 , May 2004 , pp. 438 - 440
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2004

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Kluytmans, J, van Belkum, A, Verbrugh, H. Nasal carriage of Staphylococcus aureus: epidemiology, underlying mechanisms, and associated risks. Clin Microbiol Rev 1997;10:505–520.CrossRefGoogle ScholarPubMed
2.Muto, CA, Jernigan, JA, Ostrowsky, BE, et al.SHEA guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and Enterococcus. Infect Control Hosp Epidemiol 2003;24:362–386.Google Scholar
3.National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility Testing: Twelfth Informational Supplement. Wayne, PA: National Committee for Clinical Laboratory Standards. M100-S12.Google Scholar
4.Pedro-Botet, ML, Modol, JM, Valles, X, et al.Changes in bloodstream infections in HIV-positive patients in a university hospital in Spain (1995-1997). Int J Infect Dis 2002;6:17–22.Google Scholar
5.Sissolak, D, Geusau, A, Heinze, G, Witte, W, Rotter, ML. Risk factors for nasal carriage of Staphylococcus aureus in infectious disease patients, including patients infected with HIV, and molecular typing of colonizing strains. Eur J Clin Microbiol Infect Dis 2002;21:88–96.Google Scholar
6.Shopsin, B, Mathema, B, Martinez, J, et al.Prevalence of methicillin-resis-tant and methicillin-susceptible Staphylococcus aureus in the community. J Infect Dis 2000;182:359–362.CrossRefGoogle ScholarPubMed
7.Sa-Leao, R, Sanches, IS, Conto, I, Alves, CR, de Lancastre, H. Low prevalence of methicillin-resistant strains among Staphylococcus aureus colonizing young and healthy members of the community in Portugal. Microb Drug Resist 2001;7:237–245.Google Scholar
8.Charlebois, ED, Bangsberg, DR, Moss, NJ, et al.Population-based community prevalence of methicillin-resistant Staphylococcus aureus in the urban poor of San Francisco. Clin Infect Dis 2002;34:425–433.Google Scholar
9.Naimi, TS, LeDell, KH, Boxrud, DJ, et al.Epidemiology and clonality of community-acquired methicillin-resistant Staphylococcus aureus in Minnesota, 1996-1998. Clin Infect Dis 2001;33:990–996.Google Scholar
10.Groom, AV, Wolsey, DH, Naimi, TS, et al.Community-acquired methicillin-resistant Staphylococcus aureus in a rural American Indian community. JAMA 2001;286:1201–1205.Google Scholar
11.Tumbarello, M, de Gaetano Donati, K, Tacconelli, E, et al.Risk factors and predictors of mortality of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia in HIV-infected patients. J Antimicrob Chemother 2002;50:375–382.Google Scholar
12.Onorato, M, Borucki, MJ, Baillargeon, G, et al.Risk factors for colonization or infection due to methicillin-resistant Staphylococcus aureus in HIV-positive patients: a retrospective case-control study. Infect Control Hosp Epidemiol 1999;20:26–30.Google Scholar
13.Smith, NP, Nelson, MR, Azadian, B, Gazzard, BG. An outbreak of methicillin-resistant Staphylococcus aureus (MRSA) infection in HIV-seroposi-tive persons. Int J STD AIDS 1998;9:726–730.Google Scholar