Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-18T08:01:09.616Z Has data issue: false hasContentIssue false
  • English
  • Français

Herpes Simplex Virus

Published online by Cambridge University Press:  02 January 2015

Bryan P. Simmons  and
Michael S. Gelfand
Bryan P. Simmons*
Affiliation:
Department of Infectious Diseases, Methodist Central Hospital, Memphis, Tennessee
Michael S. Gelfand
Affiliation:
Department of Infectious Diseases, Methodist Central Hospital, Memphis, Tennessee
*
1265 Union Avenue, Methodist Central Hospital, Memphis, TN 38104
Get access Rights & Permissions [Opens in a new window]

Abstract

Herpes simplex virus (HSV) causes a variety of illnesses in th e community and hospital settings (Table). Nosocomial infections with this virus may result from: 1) reactivation of latent infection, especially in patients whose immune systems are compromised; 2) spread from mother to infant; 3) spread from patients to hospital personnel; 4) spread from hospital personnel to patients; and 5) cross-infection among patients. The latter two possibilities seem to occur infrequently but merit some discussion because of the serious implications of such infections.

Type
Special Sections
Information
Infection Control & Hospital Epidemiology , Volume 7 , Issue 7 , July 1986 , pp. 380 - 383
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1986

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Lindgren, KM, Douglas, RG Jr, Couch, RB: Significance of Herpesvirus hominis in respiratory secretions of man. N Engl J Med 1968;278:517–523.CrossRefGoogle ScholarPubMed
2.Nahmias, AJ, Josey, WE: Epidemiology of herpes simplex viruses 1 and 2, in Evans, AS (ed): Viral Infections of Humans: Epidemiology and Control. New York, Plenum Medical Book Co, 1976, pp 253–271.CrossRefGoogle Scholar
3.Buchnan, TG, Roizman, B, Adams, G, et al: Restriction endonuclease finger-printing of herpes simplex virus DNA: A novel epidemiologic tool applied to a nosocomial outbreak. J Infect Dis 1978;138:488–498.CrossRefGoogle Scholar
4.Manzella, TB, McConville, JH, Valenti, W, et al: An outbreak of herpes simplex virus type 1 gingivostomatitis in a dental hygiene practice. JAMA 1984;252:2019–2022.CrossRefGoogle Scholar
5.Nahmias, AJ, Roizman, B: Infections with herpes simplex viruses 1 and 2. N Engl J Med 1973;289:667-674, 719-725, 781–789.CrossRefGoogle Scholar
6.Blank, H, Haines, HG: Experimental human reinfection with herpes simplex virus. J Invest Dermatol 1973;61:223–225.CrossRefGoogle ScholarPubMed
7.Muller, SA, Herrmann, EC Jr, Winkelmann, RK: Herpes simplex infections in hematologic malignancies. Am J Med 1972;52:102–114.CrossRefGoogle ScholarPubMed
8.Siegal, FP, Lopez, C, Hammer, GS, et al: Severe acquired immunodeficiency in male homosexuals, manifested by chronic perianal ulcerative herpes simplex lesions. N Engl J Med 1981;305:1439–1444.CrossRefGoogle ScholarPubMed
9.Buss, DH, Scharyj, M: Herpesvirus infection of the esophagus and other visceral organs in adults. Incidence and clinical significance. Am J Med 1979;66:457–462.CrossRefGoogle ScholarPubMed
10.Stone, WJ, Scowden, EB, Spannuth, CL, et al: Atypical herpesvirus hominis type 2 infection in uremic patients receiving immunosuppressive therapy. Am J Med 1977;63:511–516.CrossRefGoogle ScholarPubMed
11.Foley, FD, Greenwald, KA, Nash, MG, et al: Herpesvirus infection in burned patients. N Engl J Med 1970;282:652–656.CrossRefGoogle ScholarPubMed
12.Wheeler, CE Jr, Abele, DC: Eczema herpeticum, primary and recurrent. Arch Dermatol 1966;93:162–173.CrossRefGoogle ScholarPubMed
13.Nahmias, AJ, Keyersling, HL, Kerrick, GM: Herpes simplex, in Remington, JS, Klein, JO (eds): Infectious Disease of the Fetus and Newborn Infant. Philadelphia, WB Saunders, 1983, pp 636–678.Google Scholar
14.Hanshaw, JB: Herpesvirus hominis infections in the fetus and the newborn. Am J Dis Child 1973;126:546–555.Google ScholarPubMed
15.Light, IJ: Postnatal acquisition of herpes simplex virus by the newborn infant: A review of the literature. Pediatrics 1979;63:480–482.CrossRefGoogle ScholarPubMed
16.Francis, DP, Herrmann, KL, MacMahon, JR, et al: Nosocomial and maternally acquired herpesvirus hominis infections. Am J Dis Child 1975;129:889–893.CrossRefGoogle ScholarPubMed
17.Hammory, BH, Osterman, CA, Wenzel, RP: Herpetic whitlow. N Engl J Med 1975;292:268.Google Scholar
18.Rosato, FE, Rosato, EF, Plotkin, SA: Herpetic paronychia—An occupational hazard of medical personnel. N Engl J Med 1970;283:804–805.CrossRefGoogle ScholarPubMed
19.Stern, H, Elek, SD, Millar, DM, et al: Herpetic whitlow—A form of cross-infection in hospitals. Lancet 1959;2:871–874.CrossRefGoogle Scholar
20.Hambrick, GW Jr, Cox, RP, Senior, JR: Primary herpes simplex infection of fingers of medical personnel. Arch Dermatol 1962;85:583–589.CrossRefGoogle ScholarPubMed
21.Corey, L, Holmes, KK: Genital herpes simplex virus infections: Current concepts in diagnosis, therapy, and prevention. Ann Intern Med 1983;98:973–983.CrossRefGoogle ScholarPubMed
22.Solomon, AR, Rasmussen, JE, Varani, J, et al: The Tzanck smear in the diagnosis of cutaneous herpes simplex. JAMA 1984;251(5):633–635.CrossRefGoogle ScholarPubMed
23.Nerurkar, LS, Namba, M, Sever, JL: Comparison of standard tissue culture, tissue culture plus staining, and direct staining for detection of genital herpes simplex virus infection. J Clin Microbiol 1984;19(5):631–633.CrossRefGoogle ScholarPubMed
24.Land, S, Skurrie, IJ, Gilbert, GL: Rapid diagnosis of herpes simplex virus infections by enzyme-linked immunosorbent assay. J Clin Microbiol 1984;19(6):865–869.CrossRefGoogle ScholarPubMed
25.Warford, AL, Levy, RA, Rekrut, KA: Evaluation of a commercial enzyme-linked immunosorbent assay for detection of herpes simplex virus antigen. J Clin Microbiol 1984;20(3):490–493.CrossRefGoogle ScholarPubMed
26.Kibrick, S: Herpes simplex infection at term: What to do with mother, newborn, and nursery personnel. JAMA 1980;243:157–160.CrossRefGoogle Scholar
27.Williams, WW: Guideline for infection control in hospital personnel. Infect Control 1983;4:326–349.Google ScholarPubMed
28.Corey, L, Nahmias, AJ, Guinan, ME, et al: A trial of topical acyclovir in genital herpes simplex virus infections. N Engl J Med 1982;306:1313–1319.CrossRefGoogle ScholarPubMed
29.Luby, JP, Gnann, JW Jr, Alexander, WJ, et al: A collaborative study of patient-initiated treatment of recurrent genital herpes with topical acyclovir or placebo. J Infect Dis 1984;150(1):1–6.CrossRefGoogle ScholarPubMed
30.Spruance, SL, Crumpacker, CS, Schnipper, LE, et al: Early, patient-initiated treatment of herpes labialis with topical 10% acyclovir. Antimicrob Agents Chemother 1984;25(5):553–555.CrossRefGoogle ScholarPubMed
31.Bryson, YJ, Dillon, M, Lovett, M, et al: Treatment of first episodes of genital herpes simplex virus infection with oral acyclovir. N Engl J Med 1983;308:916–921.CrossRefGoogle ScholarPubMed
32.Douglas, J, Critchlow, C, Benedetti, J, et al: A double-blind study of oral acyclovir for suppression of recurrences of genital herpes simplex virus infection. N Engl J Med 1984;310:1551–1556.CrossRefGoogle ScholarPubMed
33.Straus, SE, Takiff, HE, Seidlin, M, et al: Suppression of frequently recurring genital herpes. N Engl J Med 1984;310:1545–1550.CrossRefGoogle ScholarPubMed
34.Straus, SE, Seidlin, M, Takiff, H, et al: Oral acyclovir to suppress recurring herpes simplex virus infections in immunodeficient patients. Ann Intern Med 1984;100:522–524.CrossRefGoogle ScholarPubMed
35.Wade, JC, Newton, B, Flournoy, N, et al: Oral acyclovir for prevention of herpes simplex virus reactivation after marrow transplantation. Ann Intern Med 1984;100:823–828.CrossRefGoogle ScholarPubMed
36.Straus, SE, Smith, HA, Brickman, C, et al: Acyclovir for chronic mucocutaneous herpes simplex virus infection in immunosuppressed patients. Ann Intern Med 1982;96:270–277.CrossRefGoogle ScholarPubMed
37.Balfour, HH Jr: Resistance of herpes simplex to acyclovir. Ann Intern Med 1983;98(3):404–406.CrossRefGoogle ScholarPubMed