I have been asked to remark on the instrumentation which, at least from the viewpoint of the 1980's, seems most important for early implementation on a VLT in the 1990's. To avoid simply making a long list of many possibilities, each of which has some advantage over its competitors, I will divide the discussion into three parts: a summary of the principal observational advances made possible by a VLT in the 15-20 meter class; a list of what is arguably the resulting basic set of needed instruments; and a brief consideration of the telescope design features, technology development programs, and political/financial efforts required to make those instruments a reality.