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Outcome after Asphyxial and Circulatory Disturbances in the Brain

Published online by Cambridge University Press:  10 March 2009

Malcolm I. Levene
Malcolm I. Levene
Affiliation:
Leicester Royal Infirmary
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Extract

The first consideration must be an agreed-upon definition of asphyxia. We cannot determine outcome of a condition if some observers are referring to apples and others to pears. Asphyxia is a pathophysiological event comprising both hypoperfusion and hypoxia, and these events result in compromise at a cellular level with the production of metabolic acids. This can be due to a wide number of insults, but a complication of the birth process is the most important cause. Asphyxia is not like intraventricular hemorrhage (IVH) or periventricular leukomalacia (PVL), as these are conditions that can be diagnosed with a reasonable degree of precision with imaging techniques.

Type
Neonatal Disorders of the Central Nervous System
Information
International Journal of Technology Assessment in Health Care , Volume 7 , Supplement S1 , January 1991 , pp. 113 - 117
Copyright
Copyright © Cambridge University Press 1991

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References

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