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Magnetic Resonance Imaging:Overview of the Technology and Medical Applications

Published online by Cambridge University Press:  10 March 2009

Lisa I. lezzoni ,
Oren Grad  and
Mark A. Moskowitz
Lisa I. lezzoni
Affiliation:
Boston University Medical Center
Oren Grad
Affiliation:
Massachusetts Institute of Technology
Mark A. Moskowitz
Affiliation:
Boston Unverisity Medical Center
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Extract

The physical phenomenon of nuclear magnetic resonance (NMR) was first characterized almost forty years ago in 1946 by the simultaneous but independent experimental successes of American scientists Felix Bloch and Edward Purcell. Their discoveries prompted development of conventional NMR spectroscopy. a technique used to describe the molecular composition and behavior of chemical compounds. Twenty-five years later, in 1971, Damadian used NMR to demonstrate differences in the behavior of water in malignant and benign tissues, and he suggested that NMR possessed “many of the desirable features of an external probe for the detection of internal cancer” (7). In the same year, Lauterbur produced the first two-dimensional NMR image, a cross-sectional portrait of two tubes of water (25). The potential utility of this technique to medical imaging was obvious, and soon afterwards multiple researchers began development of clinical NMR imaging systems. The first human whole-body NMR scan was accomplished by 1977. Improvements in the scanning process and image quality continue with, as yet, no limits in sight. In this clinical context, NMR techniques have experienced a name change to the current prevailing appellation, magnetic resonance imaging (MRI).

Type
An International View of Magnetic Resonance—Imaging and Spectroscopy
Information
International Journal of Technology Assessment in Health Care , Volume 1 , Issue 3 , July 1985 , pp. 481 - 498
Copyright
Copyright © Cambridge University Press 1985

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