Hostname: page-component-848d4c4894-8kt4b Total loading time: 0 Render date: 2024-07-01T10:23:32.575Z Has data issue: false hasContentIssue false

Effects of oxalic acid ingestion by sheep. I. Small doses to chaff fed sheep

Published online by Cambridge University Press:  27 March 2009

P. S. Watts
Affiliation:
Institute of Medical and Veterinary Science, Adelaide, South Australia

Extract

Small doses of oxalic acid were given to sheep and typical results in sheep receiving 3 and 6 g. per day are given in detail. Little was excreted in the faeces, although sufficient calcium was present in the faeces to combine with 12 times the amount of oxalate present. The blood urea value rose, the blood calcium fell and there was an increase in the CO2 combining power. Only very small amounts of oxalic acid were found in the tissues after death. Sheep receiving the larger dose showed typical acute changes in the kidneys with deposition of crystals. Nevertheless, little evidence of renal failure or actual obstruction was obtained, the volume of the urine being maintained and the urea concentration remaining normal.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1959

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Anon. (1951). Mitchell's Manual of Practical Biochemistry for Medical Students, 2nd ed. p. 103.Google Scholar
Archer, A. E. & Robb, G. D. (1925). Aust. J. Med. 18, 174.Google Scholar
Bull, L. B. (1929). Aust. Vet. J. 5, 60.CrossRefGoogle Scholar
Domingo, W. R. & Klyne, W. (1949). Biochem. J. 45, 400.CrossRefGoogle Scholar
Esbach, , (1937). Quoted in Chemical Methods in Clinical Medicine (Harrison), 2nd ed.London: Churchill and Co.Google Scholar
Fiske, C. H. & Subbarow, Y. (1925). J. Biol. Chem. 66, 375.CrossRefGoogle Scholar
Hickinbotham, A. R. (1931). J. Agric. S. Aust. 34, 1255.Google Scholar
King, E. J. & Armstrong, A. R. (1934). Canad. Med. Ass. J. 31, 376.Google Scholar
King, E. J., Haslewood, G. A. D. & Deloby, G. E. (1937) Lancet 1, 886. (1942) Lancet 1, 207.CrossRefGoogle Scholar
Kramer, B. & Tisdall, F. F. (1923). J. Biol. Chem. 56, 439.Google Scholar
Lewis, D. (1957). J. Agric. Sci. 48, 435.CrossRefGoogle Scholar
McCrudden, F. H. (1932). See Quantitative Clinical Chemistry Methods, 1st ed. p. 766. Baltimore, U.S.A.: Williams and Wilkins.Google Scholar
McLean, H. & De Wesselow, O. L. V. (1920). Brit. J. Exp. Path. 1, 53.Google Scholar
Schales, O. & Schales, S. S. (1941). J. Biol. Chem. 140, 879.CrossRefGoogle Scholar
Talapatra, R. K., Ray, F. C. & Sen, K. C. (1948). Indian J. Vet. Sci. no. 18, 2, 99.Google Scholar
Van Slyke, A. P. & Cullen, J. (1917). J. Biol. Chem. 30, 259.CrossRefGoogle Scholar