Hostname: page-component-7479d7b7d-8zxtt Total loading time: 0 Render date: 2024-07-12T14:06:53.260Z Has data issue: false hasContentIssue false

The final outcome of an epidemic model with several different types of infective in a large population

Published online by Cambridge University Press:  14 July 2016

Frank Ball*
Affiliation:
University of Nottingham
Damian Clancy*
Affiliation:
University of Newcastle
*
Postal address: Department of Mathematics, University of Nottingham, University Park, Nottingham NG7 2RD, UK.
∗∗Postal address: Department of Mathematics and Statistics, University of Newcastle, Newcastle upon Tyne, NEI 7RU, UK.

Abstract

We consider a stochastic model for the spread of an epidemic amongst a closed homogeneously mixing population, in which there are several different types of infective, each newly infected individual choosing its type at random from those available. The model is based on the carrier-borne model of Downton (1968), as extended by Picard and Lefèvre (1990). The asymptotic distributions of final size and area under the trajectory of infectives are derived as the initial population becomes large, using arguments based on those of Scalia-Tomba (1985), (1990). We then use our limiting results to compare the asymptotic final size distribution of our model with that of a related multi-group model, in which the type of each infective is assigned deterministically.

Type
Research Papers
Copyright
Copyright © Applied Probability Trust 1995 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Work carried out in part while Damian Clancy was supported by an SERC research studentship at the University of Nottingham.

References

Andersson, H. (1993) A threshold limit-theorem for a multitype epidemic model. Math. Biosci. 117, 318.Google Scholar
Andersson, H. and Djehiche, B. (1994) A functional limit theorem for the total cost of a multitype standard epidemic. Adv. Appl. Prob. 26, 690697.Google Scholar
Von Bahr, B. and Martin-Löf, A. (1980) Threshold limit theorems for some epidemic processes. Adv. Appl. Prob. 12, 319349.Google Scholar
Ball, F. G. (1983) The threshold behaviour of epidemic models. J. Appl. Prob. 20, 227241.Google Scholar
Ball, F. G. (1990) A new look at Downton's carrier-borne epidemic model. In Stochastic Processes in Epidemic Theory, ed. Gabriel, J. P., Lefèvre, C. and Picard, P., Lecture Notes in Biomathematics 86, pp. 7185. Springer-Verlag, Berlin.Google Scholar
Ball, F. G. and Clancy, D. (1993) The final size and severity of a generalised stochastic multitype epidemic model. Adv. Appl. Prob. 25, 721736.Google Scholar
Clancy, D. (1993) Epidemic models in heterogeneous populations. , University of Nottingham.Google Scholar
Donnelly, P. (1993) The correlation structure of epidemic models. Math. Biosci. 117, 4975.Google Scholar
Downton, F. (1968) The ultimate size of carrier-borne epidemics. Biometrika 55, 277289.Google Scholar
Ethier, S. N. and Kurtz, T. G. (1986) Markov Processes: Characterization and Convergence. Wiley, New York.Google Scholar
Martin-Löf, A. (1986) Symmetric sampling procedures, general epidemic processes, and their threshold limit theorems. J. Appl. Prob. 23, 265282.Google Scholar
Martin-Löf, A. (1990) Threshold limit theorems in the theory of rumors, snowball sampling and epidemics. In Stochastic Processes in Epidemic Theory, ed. Gabriel, J. P., Lefèvre, C. and Picard, P, Lecture Notes in Biomathematics 86, pp. 184188. Springer-Verlag, Berlin.Google Scholar
Picard, P. and Lefevre, C. (1990) A unified analysis of the final size and severity distribution in collective Reed-Frost epidemic processes. Adv. Appl. Prob. 22, 269294.Google Scholar
Scalia-Tomba, G. (1985) Asymptotic final size distribution for some chain-binomial processes. Adv. Appl. Prob. 17, 477495.Google Scholar
Scalia-Tomba, G. (1986) Asymptotic final size distribution of the multitype Reed-Frost process. J. Appl. Prob. 23, 563584.Google Scholar
Scalia-Tomba, G. (1990) On the asymptotic final size distribution of epidemics in heterogeneous populations. In Stochastic Processes in Epidemic Theory, ed. Gabriel, J. P., Lefèvre, C. and Picard, P., Lecture Notes in Biomathematics 86, pp. 189196. Springer-Verlag, Berlin.Google Scholar
Sellke, T. (1983) On the asymptotic distribution of the size of a stochastic epidemic. J. Appl. Prob. 20, 390394.CrossRefGoogle Scholar
Svensson, A. (1993) On the simultaneous distribution of size and costs of an epidemic in a closed multigroup population. Research report 1993:2, Department of Statistics, Stockholm University.Google Scholar