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Un modele probabiliste utile en biologie moleculaire

Published online by Cambridge University Press:  14 July 2016

Anatole Joffe*
Affiliation:
Université de Montréal
*
Adresse postale: Centre de recherche de mathématiques appliquées, Université de Montréal, Case postale 6128, succ. “A”, Montréal, Qué. H3C 3J7, Canada.

Abstract

Let X1 ··· Xn be i.i.d.r.v.'s uniformly distributed on [0, l]. Let X(1) ··· X(n) be the ordered r.v.'s 0≦ X(1)X(2)···≦ X(n)l. We obtain the n + 1 intervals (X(i), X(i+1))ni=0, with X(0) = 0, X(n+1)= l of length Li = X(i+1)X(i). Let N(c) be the number of intervals of length Li < c. We have where The study of Nc is of some interest in molecular biology and was studied in [3] where the author found a complicated expression for the probability for a randomly chosen segment to have a length less than or equal to c; he then obtains an approximation. From the experimental point of view, it seems more reasonable to work with the mean since one can obtain an unbiased estimator that way.

Type
Short Communications
Copyright
Copyright © Applied Probability Trust 1982 

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Footnotes

Ce travail a été subventionné par le programme FCAC du Ministère de l'Education du Québec et par une subvention du Conseil de recherches en sciences naturelles et en génie du Canada.

References

Bibliographie

[1] De Finetti, B. (1964) Alcune osservatzioni in tema di ‘suddivisione casuale’. Giorn. Ist. Ital. Attuari 27, 151173.Google Scholar
[2] Feller, W. (1966) An Introduction to Probability Theory and its Applications, Vol. 2. Wiley, New York.Google Scholar
[3] Litwin, S. (1969) The distribution of radioactive recovery in randomly cut and sedimented DNA. J. Appl. Prob. 6, 275284.Google Scholar
[4] Stevens, W. L. (1939) Solution to a geometric problem in probability. Ann. Eugenics 2, 315320.Google Scholar