Hostname: page-component-7bb8b95d7b-dvmhs Total loading time: 0 Render date: 2024-09-16T21:50:56.742Z Has data issue: false hasContentIssue false

428. The acid phosphatase of mammary tissue of the cow and the rat

Published online by Cambridge University Press:  01 June 2009

J. E. C. Mullen
Affiliation:
National Institute for Research in Dairying, University of Reading

Extract

1. Mammary tissue of the cow and the rat contains acid phosphatase. The respective pH optima are 5·5–5·8 and 6·0.

2. The enzyme in cow mammary tissue is probably one of type AII in the Folley & Kay (10) classification.

3. The acid phosphatase of cow mammary tissue is inhibited by a factor in raw cows' milk. This factor is destroyed by heat.

4. On the basis of rate of hydrolysis of phenylphosphate at the optimum pH there is about 5 times more alkaline phosphatase in the mammary tissue of the cow than acid phosphatase.

5. The effect of adrenalectomy and replacement therapy through the administration of cortical steroids has no marked effect on the acid phosphatase of rat mammary tissue.

Type
Original Articles
Copyright
Copyright © Proprietors of Journal of Dairy Research 1950

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

(1)Grernstrin, J. P. (1942). J. nat. Canc. Inst. 2, 511.Google Scholar
(2)Dempsey, E. W., Bunting, H. & Wislocki, G. B. (1947). Amer. J. Anal. 81, 309.CrossRefGoogle Scholar
(3)Caputto, R. & Marsal, A. (1941). Rev. Soc. argent. Biol. 17, 139.Google Scholar
(4)Folley, S. J. & Kay, H. D. (1935). Biochem. J. 29, 1837.CrossRefGoogle Scholar
(5)Folley, S. J. & Greenbaum, A. L. (1947). Biochem. J. 41, 261.CrossRefGoogle Scholar
(6)Folley, S. J. & Watson, S. C. (1948). Biochem. J. 42, 204.CrossRefGoogle Scholar
(7)Folley, S. J. & Cowie, A. T. (1944). Yale J. biol. Med. 17, 67.Google Scholar
(8)Gutman, E. B. & Gutman, A. B. (1940). J. biol. Chem. 136, 201.CrossRefGoogle Scholar
(9)Sumner, J. B. (1944). Science, 100, 413.CrossRefGoogle Scholar
(10)Folley, S. J. & Kay, H. D. (1936). Ergebn. Enzymforsch. 5, 159.Google Scholar
(11)Mullen, J. E. C. (1950). J. Dairy Res. 17, 288.CrossRefGoogle Scholar
(12)Folley, S. J. & Greenbaum, A. L. (1946). Biochem. J. 40, 46.CrossRefGoogle Scholar