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Evaluation of the serum fructosamine test to monitor plasma glucose concentration in the transition dairy cow

Published online by Cambridge University Press:  05 January 2009

María L Sorondo  and
Alberto Cirio
María L Sorondo
Affiliation:
Departamento de Patología y Clínica de Rumiantes y Suinos, Alberto Lasplaces 1550, Montevideo 11600, Uruguay
Alberto Cirio*
Affiliation:
Departamento de Fisiología, Facultad de Veterinaria, Alberto Lasplaces 1550, Montevideo 11600, Uruguay
*
*For correspondence; e-mail: albertocirio@yahoo.com
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Abstract

The usefulness of the serum fructosamine (Fser) to monitor the retrospective glucose concentrations in transitional dairy cows (n=17) was evaluated. In weekly blood samples (3 weeks before to 5 weeks after calving) concentrations of plasma glucose and serum fructosamine, β-hydroxybutyrate (βOHB) and total proteins were determined. The observed Fser concentrations (271±55 mean value, range 152–423 μmol/l) were within the range reported in the literature, and showed a progressive and significant decrease after calving. Mean plasma glucose concentration was 60·6±5·0 (range 39·9–82·2) mg/dl increasing from week 3 before calving to the week of calving and then decreasing during the next 5 weeks of lactation. This decrease was coincident with inverse relationships between plasma glucose and milk yield (P=0·03) and serum βOHB (P<0·001). Linear regression analysis performed between serum fructosamine and (a) plasma glucose concentration of the same sampling and (b) plasma glucose concentration of 1, 2 and 3 weeks preceding the sampling, did not show significant and systematizing positive correlations. Persistent hypoproteinaemias that could affect the fructosamine concentrations were not found: mean value and range of serum proteins was 6·3±1·0 and 4·8–7·8 g/dl, respectively, and no correlation was found between serum proteins and Fser (P=0·26). Results did not support the possibility of retrospective monitoring of the plasma glucose concentration by serum fructosamine in dairy cows in the transition period.

Keywords

Serum fructosamineplasma glucosedairy cowtransition period
Type
Research Article
Information
Journal of Dairy Research , Volume 76 , Issue 2 , May 2009 , pp. 173 - 178
Copyright
Copyright © Proprietors of Journal of Dairy Research 2008

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References

Armbruster, DA 1987 Fructosamine: structure, analysis and clinical usefulness. Clinical Chemistry 33 2153–2163CrossRefGoogle ScholarPubMed
Brandon, MR, Watson, DL & Lascelles, AK 1971 The mechanism of transfer of immunoglobulins into mammary secretion of cows. Australian Journal of Experimental Biology & Medical Sciences 49 613–623CrossRefGoogle ScholarPubMed
Ceballos, A, Gómez, PM, Vélez, ML, Villa, NA & López, LF 2002a [Variation in biochemical indicators of energy balance in relation to production in dairy cows in Manizales, Colombia]. Revista Colombiana de Ciencias Pecuarias 15 13–25Google Scholar
Ceballos, A, Villa, NA, Andaur, M, Gómez, PM, Vélez, ML, Escobar, DM, Osorio, M, Loaiza, J & Wittwer, F 2002b Serum fructosamine concentration during the transitional period in Holstein and Brahman cows. Proceedings of the 10th Congress of the International Society of Animal Clinical Biochemistry Gainesville, Florida.Google Scholar
Chilliard, Y 1987 [Literature review: Quantitative variations in lipid metabolism in adipose tissue and liver during the gestation-lactation cycle. Part 2: cows and ewes]. Reproduction, Nutrition, Développement 27 327–398CrossRefGoogle Scholar
Coppo, JA 2001 Evolution of fructosaminaemia and glucaemia during the growth of unweaned and early weaned half-bred Zebu calves. Veterinary Research Communications 25 449–459CrossRefGoogle ScholarPubMed
Coppo, JA & Mussart de Coppo, NB 1997 [Glycosylation of blood proteins as a retrospective evaluation of glycaemia. Applications in veterinary medicine]. Revista de Medicina Veterinaria 78 292–295Google Scholar
Cornelius, CE, Baker, NF, Kaneko, JJ & Douglas, JR 1962 Distribution and turnover of iodine-131-tagged bovine albumin in normal and parasitized cattle. American Journal of Veterinary Research 23 837–842Google ScholarPubMed
de Boer, G, Trenkle, A & Young, JW 1985 Glucagon, insulin, growth hormone, and some blood metabolites during energy restriction ketonemia of lactating cows. Journal of Dairy Science 68 326–337CrossRefGoogle ScholarPubMed
Đoković, R, Šamanc, H & Bošković-Bogosavljević, S 2003 Blood concentration of free fatty acids, glucose and insulin in high producing dairy cows during the peripartum period. Veterinarski Glasnik 57 405–413Google Scholar
Harrison, RO, Ford, SP, Young, JW, Conley, AJ & Freeman, AE 1990 Increased milk production versus reproductive and energy status of high producing dairy cows. Journal of Dairy Science 73 2749–2758CrossRefGoogle ScholarPubMed
Jensen, AL 1993 Various proteins and albumin corrections of the serum fructosamine concentration in the diagnosis of canine diabetes mellitus. Veterinary Research Communications 17 13–23CrossRefGoogle ScholarPubMed
Jensen, AL 1995 Glycated blood proteins in canine diabetes mellitus. Veterinary Record 137 401–405CrossRefGoogle ScholarPubMed
Jensen, AL, Petersen, MB & Houe, H 1993 Determination of fructosamine concentration in bovine serum samples. Journal of Veterinary Medicine 40 111–117CrossRefGoogle ScholarPubMed
Jordán, D, Villa, NA, Gutiérrez, M, Gallego, AB, Ochoa, GA & Ceballos, A 2006 [Biochemical indicators in blood of fighting cattle maintained on mountain pasture in central Colombia]. Revista Colombiana de Ciencias Pecuarias 19 18–26Google Scholar
Jorritsma, R, Wensing, T, Kruip, TAM, Vos, PLAM & Noordhuizen, JPTM 2003 Metabolic changes in early lactation and impaired reproductive performance in dairy cows. Veterinary Research 34 11–26CrossRefGoogle ScholarPubMed
Kawamoto, M, Kaneko, JJ, Heusner, AA, Feldman, EC & Koizumi, I 1992 Relation of fructosamine to serum protein, albumin, and glucose concentrations in healthy and diabetic dogs. American Journal of Veterinary Research 53 851–855CrossRefGoogle ScholarPubMed
Larson, BL & Kendall, KA 1957 Changes in specific blood serum protein levels associated with parturition in the bovine. Journal of Dairy Science 40 659–666CrossRefGoogle Scholar
Marca, MC, Loste, A & Ramos, JJ 2000 Effect of acute hyperglycaemia on the serum fructosamine and blood glycated haemoglobin concentrations in canine samples. Veterinary Research Communications 24 11–16CrossRefGoogle ScholarPubMed
Ndibualonji, BB, Dehareng, D & Godeau, JM 1995 [Under feeding in energy and nitrogen in the cow. Effects on rumen volatile fatty acids, some plasma hormones and metabolites and the excretion of 3-methylhistidine]. Reproduction Nutrition Development 35 137–154CrossRefGoogle Scholar
Reusch, CE, Liehs, MR, Hoyer, M & Vochezer, R 1993 Fructosamine. A new parameter for diagnosis and metabolic control in diabetic dogs and cats. Journal of Veterinary Internal Medicine 7 177–182CrossRefGoogle ScholarPubMed
Ropstad, E 1987 Serum fructosamine levels in dairy cows related to metabolic status in early lactation. Acta Veterinaria Scandinavica 28 291–298Google ScholarPubMed
Ropstad, E 1991 Constituents of blood and milk in relation to fertility, nutrition and metabolic status in dairy cows. Veterinary Bulletin 61 1106Google Scholar
The Merck Veterinary Manual 1998 8th Edn p 2190 (Ed.Aiello, SE) NJ, USA: Merck & Co IncGoogle Scholar
Voziyan, PA, Khalifa, RG, Thibaudeau, C, Yildiz, A, Jacob, J, Serianni, AS & Hudson, BG 2003 Modification of proteins in vitro by physiological levels of glucose. Pyridoxamine inhibits conversion of Amadori intermediate to advanced glycation end-products through binding of redox metal ions. Journal of Biological Chemistry 278 46616–46624CrossRefGoogle ScholarPubMed
Willms, B & Lehmann, P 1990 A new fructosamine-test as a routine parameter in diabetes monitoring. Wiener Klinische Wochenschrift Supplement 180 102 5–10Google Scholar