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Identification of a new molecular form of human α-lactalbumin

Published online by Cambridge University Press:  01 June 2009

Françoise Maynard
Françoise Maynard
Affiliation:
Laboratoire de Recherches de Technologie Laitière, INRA, 65 rue de Saint-Brieuc, 35042 Rennes, France
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Extract

α-Lactalbumin (α-La) is a protein found in the milk of all mammalian species and is involved in lactose biosynthesis in association with galactosyltransferase (Brodbeck et al. 1967). The primary structure of α-La from several species such as bovine (Brew et al. 1970), human (Findlay & Brew, 1972), and goat (McGillivray et al. 1979) has been determined. Hall et al. (1982) have established the nucleotide sequence and the organization of the human α-La gene (Hall et al. 1987).

Type
Short Communications
Information
Journal of Dairy Research , Volume 59 , Issue 3 , August 1992 , pp. 425 - 429
Copyright
Copyright © Proprietors of Journal of Dairy Research 1992

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References

REFERENCES

Barman, T. E. 1970 Purification and properties of bovine milk glyco-α-lactalbumin. Biochimica et Biophysica Acta 214 242–244CrossRefGoogle ScholarPubMed
Barman, T. E. 1973 The isolation of an α-lactalbumin with three disulphide bonds. European Journal of Biochemistry 37 86–89CrossRefGoogle ScholarPubMed
Bell, K., Hopper, K. E., McKenzie, H. A., Murphy, W. H. & Shaw, D. C. 1970 A comparison of bovine α-lactalbumin A and B of Droughtmaster. Biochimica et Biophysica Acta 214 437–444CrossRefGoogle Scholar
Bigelow, C. C. 1967 On the average hydrophobicity of proteins and the relation between it and protein structure. Journal of Theoretical Biology 16 187–211CrossRefGoogle ScholarPubMed
Brew, K., Castellino, F. J., Vanaman, T. C. & Hill, R. L. 1970 The complete amino-acid sequence of bovine α-lactalbumin. Journal of Biological Chemistry 245 4570–4582CrossRefGoogle ScholarPubMed
Brodbeck, U., Denton, W. L., Tanahashi, N. & Ebner, K. E. 1967 The isolation and identification of the B protein of lactose synthetase as α-lactalbumin. Journal of Biological Chemistry 242 1391–1397CrossRefGoogle Scholar
Findlay, J. B. C. & Brew, K. 1972 The complete amino-acid sequence of human α-lactalbumin. European Journal of Biochemistry 27 65–86CrossRefGoogle Scholar
Hall, L., Craig, R. K., Edbrooke, M. R. & Campbell, P. N. 1982 Comparison of the nucleotide sequence of cloned human and guinea-pig pre-α-lactalbumin cDNA with that of chick pre-lysozyme cDNA suggests evolution from a common ancestral gene. Nucleic Acids Research 10 3503–3515CrossRefGoogle ScholarPubMed
Hall, L., Emery, D. C., Davies, M. S., Parker, D. & Craig, R. K. 1987 Organization and sequence of the human α-lactalbumin gene. Biochemical Journal 242 735–742CrossRefGoogle ScholarPubMed
Hopper, K. E. & McKenzie, H. A. 1973 Minor components of bovine α-lactalbumin A and B. Biochimica et Biophysica Acta 295 352–363CrossRefGoogle ScholarPubMed
Keil, B. 1982 Enzymic cleavage of proteins. In Methods in Protein Sequence Analysis pp. 201–304 (Ed. Elzynga, Marshall). Clifton, NJ: Humana PressGoogle Scholar
McGillivray, R. T. A., Brew, K. & Barnes, K. 1979 The amino acid sequence of goat α-lactalbumin. Archives of Biochemistry and Biophysics 197 404–414CrossRefGoogle Scholar
Maynard, F., Pierre, A. & Maubois, J. L. 1989 [Fractionation of human lactoferrin and α-lactalbumin using microfiltration and ultrafiltration membranes.] Lait 69 59–69CrossRefGoogle Scholar
Schmidt, D. V. & Ebner, K. E. 1972 Multiple forms of pig, sheep and goat α-lactalbumin. Biochimica et Biophysica Acta 263 714–720CrossRefGoogle Scholar
Vanaman, T. C., Brew, K. & Hill, R. L. 1970 The disulfide bonds of bovine α-lactalbumin. Journal of Biological Chemistry 245 4583–4590CrossRefGoogle ScholarPubMed