A decaying compressible nearly homogeneous and nearly isotropic grid-generated turbulent flow has been set up in a large scale shock tube research facility. Experiments have been performed using instrumentation with spatial resolution of the order of 7 to 26 Kolmogorov viscous length scales. A variety of turbulence-generating grids provided a wide range of turbulence scales with bulk flow Mach numbers ranging from 0.3 to 0.6 and turbulent Reynolds numbers up to 700. The decay of Mach number fluctuations was found to follow a power law similar to that describing the decay of incompressible isotropic turbulence. It was also found that the decay coefficient and the decay exponent decrease with increasing Mach number while the virtual origin increases with increasing Mach number. A possible mechanism responsible for these effects appears to be the inherently low growth rate of compressible shear layers emanating from the cylindrical rods of the grid. Measurements of the time-dependent, three dimensional vorticity vectors were attempted for the first time with a 12-wire miniature probe. This also allowed estimates of dilatation, compressible dissipation and dilatational stretching to be obtained. It was found that the fluctuations of these quantities increase with increasing mean Mach number of the flow. The time-dependent signals of enstrophy, vortex stretching/tilting vector and dilatational stretching vector were found to exhibit a rather strong intermittent behaviour which is characterized by high-amplitude bursts with values up to 8 times their r.m.s. within periods of less violent and longer lived events. Several of these bursts are evident in all the signals, suggesting the existence of a dynamical flow phenomenon as a common cause.