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The Development of Acquired Resistance and Age Resistance to Nematodirus battus in the Laboratory Rabbit

Published online by Cambridge University Press:  18 November 2009

G. J. Gallie
G. J. Gallie
Affiliation:
Parasitoiogy Department, Moredun Research Institute, Gilmerton, Edinburgh 9
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Extract

Four groups of 8 rabbits were infected with a range of doses of N. bath's larvae. The percentage recoveries of worms from groups receiving 100 and 1000 larvae were significantly greater than those from groups receiving 10000 and 50000 larvae. It is suggested that the worm population density is dependent on the degree of host response stimulated by the initial larval dose.

Experience of a chemically abbreviated patent infection of N. batlus gave significant protection to a group of 8 rabbits against establishment of worms from subsequent challenge compared with inexperienced controls.

Rabbits aged 5 months and 11 weeks were as susceptible to the establishment of worms as rabbits aged 7½ weeks; but age resistance vas manifested by the greater proportion of worms which developed to the fifth stage in the worm populations of the youngest group than in the other 2 groups.

Type
Research Article
Information
Journal of Helminthology , Volume 47 , Issue 4 , December 1973 , pp. 369 - 376
Copyright
Copyright © Cambridge University Press 1973

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References

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