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The effects of treatment with transfer factor, parasitic antigen and precipitated immunoglobulin on the parasitological and histopathological responses in Haemonchus contortus infection in lambs under six months of age

Published online by Cambridge University Press:  18 November 2009

Grace MacKenzie ,
A. R. Hunter  and
J. G. Ross
Grace MacKenzie
Affiliation:
Ministry of Agriculture, Fisheries and Food Veterinary Laboratory, Eskgrove, Lasswade, Midlothian, Scotland
A. R. Hunter
Affiliation:
Ministry of Agriculture, Fisheries and Food Veterinary Laboratory, Eskgrove, Lasswade, Midlothian, Scotland
J. G. Ross
Affiliation:
Ministry of Agriculture, Fisheries and Food Veterinary Laboratory, Eskgrove, Lasswade, Midlothian, Scotland
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Abstract

In lambs under six months of age infected with 10,000 H. contortus third stage larvae two effects were observed as a result of the treatment regimes administered: 1. Reduced adult worm burdens, indicating protection, occurred in the animals treated with combined transfer factor, adult parasitic antigen and precipitated immunoglobulin whereas other treatment combinations produced no significant effects. 2. Defined patterns of histological changes in the abomasa were associated with each treatment and cumulative effects were recognized when combined treatments were given. The responses induced by transfer factor treatment suggest the development of a hypersensitivity reaction outwith the changes seen in primary H. contortus challenge.

Type
Research Papers
Information
Journal of Helminthology , Volume 56 , Issue 4 , December 1982 , pp. 305 - 313
Copyright
Copyright © Cambridge University Press 1982

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