Hostname: page-component-6d856f89d9-72csx Total loading time: 0 Render date: 2024-07-16T06:15:47.307Z Has data issue: false hasContentIssue false

Studies on Spirometra theileri (Baer, 1925) n. comb. 3. Acquired immunity to reinfection with plerocercoids in mice

Published online by Cambridge University Press:  05 June 2009

E. K. Opuni
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, London WCIE 7HT
R. L. Muller
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, London WCIE 7HT

Abstract

100 male T.O. strain laboratory mice were divided into 4 equal groups: (I) 25 were injected intramuscularly with an antigen prepared together with Freund's adjuvant; (II) 25 injected with antigen alone; (III) 25 infected subcutaneously with 8 live plerocercoids of the same species; (IV) 25 served as controls. 4 weeks later all mice were given 6 live plerocercoids orally. The presence of acquired immunity in group III was shown by a significant reduction in the numbers, size and motility of challenge worms. The host response was greater in all the immunized groups than in the controls.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1975

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Lendrum, A.C. (1944) The staining of eosinophil polymorphs and enterochromaflin cells in hitological sections. Journal ofPathology and Bacteriology, 56, 441.CrossRefGoogle Scholar
Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951) Protein measurements with the Folin phenol reagent. Journal of Biological Chemistry, 193, 265.CrossRefGoogle ScholarPubMed
Mueller, J.F. (1969) Acquired immunity to infection with the cestode Spirometra mansonoldes. Journal of Parasitology, 55, 167170.CrossRefGoogle ScholarPubMed
Mueller, J.F. (1961) The laboratory propagation of Spirometra mansonoldes as an experimental tool. V. Behaviour of the sparganum in and out of the mouse host, and formation of an immune precipitate. Journal of Parasitology, 53, 437443.Google Scholar
Mueller, J.F. (1938) The life history of Diphyllobothrium mansonoides Mueller, 1935 and some considerations with regard to sparganosis in the United States. American Journal of tropical Medicine, 18, 4146.Google Scholar
Mueller, J.F. and Chapman, O.D. (1937) Resistance and immunity in infections with Sparganum mansonoides. Journal of Parasitology, 23, 561565.Google Scholar
Opuni, E.K. and Muller, R.L. (1974) Studies on Spirometra theileri (Baer, 1925) n. comb. 1. Identification and biology in the laboratory. Journal of Helminthology, 48, 1523.CrossRefGoogle ScholarPubMed
Rickard, M.D. and Bell, K.J. (1971) Induction of immunity in lambs to a larval cestode by diffusible antigens. Nature, London, 232, 120.CrossRefGoogle ScholarPubMed
Silverman, P.H. and Hullard, T.J. (1961) Histological observations on bovine cysticercosis. Researches in Veterinary Science, 2, 248252.CrossRefGoogle Scholar
Weinmann, C.J. (1970) Cestodes and Acanthocephala. In Immunity to parasitic animals. (Jackson, G.J., Herman, R. and Singer, I., eds.). 2, New York: Appleton-Century-Crofts.Google Scholar
Weinmann, C.J. (1965) Immunity mechanisms in cestode infections. In Biology of parasites (Soulsby, E.J.L., ed.). New York: Academic Press Inc.Google Scholar