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The effect of controlled release copper sulphate and tributyltin fluoride on the mortality and infectivity of Schistosoma mansoni cercariae

Published online by Cambridge University Press:  18 November 2009

Vithoon Viyanant
Affiliation:
Department of Biology, Faculty of Science, Mahidol University, Bangkok 4, Thailand
Sanam Thirachantra
Affiliation:
Department of Biology, Faculty of Science, Mahidol University, Bangkok 4, Thailand
Santasiri Sornmani
Affiliation:
Department of Biology, Faculty of Science, Mahidol University, Bangkok 4, Thailand

Abstract

Mortality and infectivity or Schistosoma mansoni cercariae were tested against various concentrations of controlled release copper sulphate (EC-8) and tributyltin fluoride (CBL-9B). The results indicate that survival of cercariae varied with concentrations of molluscicide and times of exposures. Statistical analysis reveals that LC50 and LC90 for EC-8 were 1·8mg/1/hour and 1·82 mg/1/hour while LC50 and LC90 for CBL-9B were 16·8 μg/1/hour and 21·7 μg/1/hour respectively. Sublethal concentration of both molluscicides reduced cercarial infectivity considerably. The doses of 0·25 to 0·5 mg/1/hour for EC-8 and 2·0 to 6·0 μg/1/hour for CBL-9B were found to be sufficient to inhabit cercarial penetration of the host skin.

Type
Research Papers
Copyright
Copyright © Cambridge University Press 1982

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